[HTML][HTML] Repurposed itraconazole for use in the treatment of malignancies as a promising therapeutic strategy
CL Li, ZX Fang, Z Wu, YY Hou, HT Wu, J Liu - Biomedicine & …, 2022 - Elsevier
Understanding cancer biology and the development of novel agents for cancer treatment
has always been the goal of cancer researchers. However, the research and development of …
has always been the goal of cancer researchers. However, the research and development of …
[HTML][HTML] Repurposing antifungal drugs for cancer therapy
N Weng, Z Zhang, Y Tan, X Zhang, X Wei… - Journal of Advanced …, 2023 - Elsevier
Background Repurposing antifungal drugs in cancer therapy has attracted unprecedented
attention in both preclinical and clinical research due to specific advantages, such as safety …
attention in both preclinical and clinical research due to specific advantages, such as safety …
Cancer metabolism as a therapeutic target and review of interventions
Cancer is amenable to low-cost treatments, given that it has a significant metabolic
component, which can be affected through diet and lifestyle change at minimal cost. The …
component, which can be affected through diet and lifestyle change at minimal cost. The …
[HTML][HTML] The roles and mechanisms of the lncRNA-miRNA axis in the progression of esophageal cancer: a narrative review
T Huang, Z Wu, S Zhu - Journal of thoracic disease, 2022 - ncbi.nlm.nih.gov
Methods Related articles published in the PubMed database between 05/30/2008 to
09/10/2022 were identified using the following terms:“lncRNA AND miRNA AND esophageal …
09/10/2022 were identified using the following terms:“lncRNA AND miRNA AND esophageal …
First-line gemcitabine, nab-paclitaxel, and oxaliplatin chemotherapy with itraconazole in patients with metastatic pancreatic cancer: a single institution experience
M Sawasaki, H Tsubamoto, A Sugihara… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Combination chemotherapy with gemcitabine, nab-paclitaxel, oxaliplatin,
and itraconazole (GnPO-ITC) was administered as first-line chemotherapy in patients with …
and itraconazole (GnPO-ITC) was administered as first-line chemotherapy in patients with …
Itraconazole inhibits the growth of cutaneous squamous cell carcinoma by targeting HMGCS1/ACSL4 axis
C Xu, Y Zhuo, Y Liu, H Chen - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Cutaneous squamous cell carcinoma (cSCC) is a common cutaneous cancer
with increasing incidence. Itraconazole has been identified as a potential anticancer drug …
with increasing incidence. Itraconazole has been identified as a potential anticancer drug …
Mdact: A new principle of adjunctive cancer treatment using combinations of multiple repurposed drugs, with an example regimen
Simple Summary We present eight core attributes of cancer growth that we must address for
a more effective treatment than we currently have. To do this we outline why a regimen …
a more effective treatment than we currently have. To do this we outline why a regimen …
Hedgehog pathway and its inhibitors in chronic obstructive pulmonary disease (COPD)
COPD affects millions of people and is now ranked as the third leading cause of death
worldwide. This largely untreatable chronic airway disease results in irreversible destruction …
worldwide. This largely untreatable chronic airway disease results in irreversible destruction …
Human umbilical cord mesenchymal stem cells: Heralding an effective treatment against esophageal cancer?
R ArefNezhad, F Rezaei‐Tazangi… - Cell Biology …, 2023 - Wiley Online Library
Esophageal cancer (EC), as one of the leading causes of cancer‐associated mortality,
influences a remarkable population of subjects globally and is histologically divided into two …
influences a remarkable population of subjects globally and is histologically divided into two …
Itraconazole Reversing Acquired Resistance to Osimertinib in NSCLC by Inhibiting the SHH/DUSP13B/p‐STAT3 Axis
H Zheng, Y Tang, H Zang, J Luo, H Zhou… - Advanced …, 2024 - Wiley Online Library
There is an urgent necessity to devise efficient tactics to tackle the inevitable development of
resistance to osimertinib, which is a third‐generation epidermal growth factor receptor …
resistance to osimertinib, which is a third‐generation epidermal growth factor receptor …