Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters

AL Bianchi, M Denavit-Saubié… - Physiological …, 1995 - journals.physiology.org
I. INTRODUCTION glossal motoneurons for genioglossus muscle that governs tongue
protrusion in inspiration (2'76, 333, 495); 2) naso-In mammals, the uptake of oxygen and …

[HTML][HTML] Pontine mechanisms of respiratory control

M Dutschmann, TE Dick - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
Pontine respiratory nuclei provide synaptic input to medullary rhythmogenic circuits to shape
and adapt the breathing pattern. An understanding of this statement depends on …

Neural regulation of respiration: rhythmogenesis and afferent control

DW Richter - … human physiology: from cellular mechanisms to …, 1996 - Springer
The primary function of respiration is to exchange gases between the external environment
and the internal milieu of the organism. Gas exchange occurs through coordinated action of …

Neuropharmacology of control of respiratory rhythm and pattern in mature mammals

A Haji, R Takeda, M Okazaki - Pharmacology & therapeutics, 2000 - Elsevier
This review summarizes the current understanding of the neurotransmitters and
neuromodulators that are involved, firstly, in respiratory rhythm and pattern generation …

Pontine respiratory activity involved in inspiratory/expiratory phase transition

M Mörschel, M Dutschmann - … Transactions of the …, 2009 - royalsocietypublishing.org
Control of the timing of the inspiratory/expiratory (IE) phase transition is a hallmark of
respiratory pattern formation. In principle, sensory feedback from pulmonary stretch …

[HTML][HTML] Control of breathing by interacting pontine and pulmonary feedback loops

YI Molkov, BJ Bacak, TE Dick, IA Rybak - Frontiers in neural circuits, 2013 - frontiersin.org
The medullary respiratory network generates respiratory rhythm via sequential phase
switching, which in turn is controlled by multiple feedbacks including those from the pons …

[HTML][HTML] The cellular building blocks of breathing

JM Ramirez, A Doi, AJ Garcia III, FP Elsen… - Comprehensive …, 2012 - ncbi.nlm.nih.gov
Respiratory brainstem neurons fulfill critical roles in controlling breathing: they generate the
activity patterns for breathing and contribute to various sensory responses including …

Learning to breathe: control of the inspiratory–expiratory phase transition shifts from sensory‐to central‐dominated during postnatal development in rats

M Dutschmann, M Mörschel, IA Rybak… - The Journal of …, 2009 - Wiley Online Library
The hallmark of the dynamic regulation of the transitions between inspiration and expiration
is the timing of the inspiratory off‐switch (IOS) mechanisms. IOS is mediated by pulmonary …

Excitatory and inhibitory synaptic inputs shape the discharge pattern of pump neurons of the nucleus tractus solitarii in the rat

M Miyazaki, I Tanaka, K Ezure - Experimental brain research, 1999 - Springer
The second-order relay neurons of the slowly-adapting pulmonary stretch receptors (SARs)
are called pump neurons (P cells) and are located in the nucleus tractus solitarii (NTS). We …

Inhibitions mediated by glycine and GABAA receptors shape the discharge pattern of bulbar respiratory neurons

K Schmid, AS Foutz, M Denavit-Saubié - Brain research, 1996 - Elsevier
Experiments were performed to identify the glycinergic or GABAergic nature, and the timing
of discharge, of the neurons which produce chloride-dependent inhibitions on other bulbar …