Glycan-based electrochemical biosensors are emerging as analytical tools for determining
multiple molecular targets relevant to diagnosing infectious diseases and detecting cancer …

Abstract Polymorphic G‐quadruplex (G4) secondary DNA structures have received
increasing attention in medicinal chemistry owing to their key involvement in the regulation …

Four hundred twenty-eight high-resolution DNA–protein complexes were chosen for a
bioinformatics study. Although 164 crystal structures (38% of those searched) contained no …

Four-stranded G-quadruplex (G4) DNA structures are promising drug targets as these non-
canonical structures appear to regulate gene expression and telomere growth. Although all …

The G‐quadruplexes (G4s) are currently being explored as therapeutic targets in cancer and
other pathologies. Six carbohydrate naphthalene diimide conjugates (carb‐NDIs) have been …

Selective G‐quadruplex ligands offer great promise for the development of anti‐cancer
therapies. A novel series of divalent cationic naphthalene diimide ligands that selectively …

A series of 1H-imidazo [4, 5-f][1, 10] phenanthroline derivatives functionalized at 2-position
with chiral, and conformationally flexible polyhydroxy alkyl chains derived from …

Here we present a novel family of carbohydrate conjugates based on the 2-aryl-imidazo [4, 5-
f][1, 10] phenanthroline core modified with carbohydrates (carb-APIPs). The hybrid …

Aptamers are single-stranded RNA or DNA molecules that specifically recognize their
targets and have proven valuable for functionalizing sensitive biosensors. α-thrombin is a …

Trioxacarcin (TXN) A was reported to be an anticancer agent through alkylation of dsDNA. G-
quadruplex DNA (G4-DNA) is frequently formed in the promoter regions of oncogenes and …