Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

The sustainable production of chemicals from renewable, nonedible biomass has emerged
as an essential alternative to address pressing environmental issues arising from our heavy …

Formate can be envisioned at the core of a carbon-neutral bioeconomy, where it is produced
from CO2 by (electro-) chemical means and converted into value-added products by …

Metabolic engineering often entails concurrent engineering of substrate utilization, central
metabolism and product synthesis pathways, inevitably creating interdependency with …

Synthetic biology aims at designing new biological functions from first principles. These new
designs allow to expand the natural solution space and overcome the limitations of naturally …

A novel biocatalytic system for the synthesis of industrially relevant C2 chemicals (eg,
ethylene glycol (3)) from formaldehyde (1) was established. The biocatalytic system …

One-carbon (C1) compounds are emerging as cost-effective and potentially carbon-negative
feedstocks for biomanufacturing, which require efficient, versatile metabolic platforms for the …

Enzymatic carbon dioxide fixation is one of the most important metabolic reactions as it
allows the capture of inorganic carbon from the atmosphere and its conversion into organic …

Abstract The chiral N‐substituted 1, 2‐amino alcohol motif is found in many natural and
synthetic bioactive compounds. In this study, enzymatic asymmetric reductive amination of α …

Artificial multi-enzyme cascades bear great potential for bioconversion of C1 compounds to
value-added chemicals. Over the past decade, massive efforts have been devoted to …