Cytokinesis in animal cells
Cytokinesis, the final step in cell division, partitions the contents of a single cell into two. In
animal cells, cytokinesis occurs through cortical remodeling orchestrated by the anaphase …
animal cells, cytokinesis occurs through cortical remodeling orchestrated by the anaphase …
Remodeling the zonula adherens in response to tension and the role of afadin in this response
Morphogenesis requires dynamic coordination between cell–cell adhesion and the
cytoskeleton to allow cells to change shape and move without losing tissue integrity. We …
cytoskeleton to allow cells to change shape and move without losing tissue integrity. We …
Phosphoinositides and cytokinesis: the “PIP” of the iceberg
A Echard - Cytoskeleton, 2012 - Wiley Online Library
Abstract Phosphoinositides [Phosphatidylinositol (PtdIns), phosphatidylinositol 3‐
monophosphate (PtdIns3P), phosphatidylinositol 4‐monophosphate (PtdIns4P) …
monophosphate (PtdIns3P), phosphatidylinositol 4‐monophosphate (PtdIns4P) …
Monitoring actin cortex thickness in live cells
Animal cell shape is controlled primarily by the actomyosin cortex, a thin cytoskeletal
network that lies directly beneath the plasma membrane. The cortex regulates cell …
network that lies directly beneath the plasma membrane. The cortex regulates cell …
Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature
In many cases, cell function is intimately linked to cell shape control. We used endothelial
cell branching morphogenesis as a model to understand the role of myosin II in shape …
cell branching morphogenesis as a model to understand the role of myosin II in shape …
Understanding the cooperative interaction between myosin II and actin cross-linkers mediated by actin filaments during mechanosensation
Myosin II is a central mechanoenzyme in a wide range of cellular morphogenic processes.
Its cellular localization is dependent not only on signal transduction pathways, but also on …
Its cellular localization is dependent not only on signal transduction pathways, but also on …
[HTML][HTML] Precise tuning of cortical contractility regulates cell shape during cytokinesis
The mechanical properties of the actin cortex regulate shape changes during cell division,
cell migration, and tissue morphogenesis. We show that modulation of myosin II (MII) …
cell migration, and tissue morphogenesis. We show that modulation of myosin II (MII) …
Molecular networks linked by Moesin drive remodeling of the cell cortex during mitosis
C Roubinet, B Decelle, G Chicanne, JF Dorn… - Journal of Cell …, 2011 - rupress.org
The cortical mechanisms that drive the series of mitotic cell shape transformations remain
elusive. In this paper, we identify two novel networks that collectively control the dynamic …
elusive. In this paper, we identify two novel networks that collectively control the dynamic …
Pharmacological activation of myosin II paralogs to correct cell mechanics defects
Current approaches to cancer treatment focus on targeting signal transduction pathways.
Here, we develop an alternative system for targeting cell mechanics for the discovery of …
Here, we develop an alternative system for targeting cell mechanics for the discovery of …
The Model Organism Dictyostelium discoideum
S Bozzaro - Dictyostelium discoideum Protocols, 2013 - Springer
Much of our knowledge of molecular cellular functions is based on studies with a few
number of model organisms that were established during the last 50 years. The social …
number of model organisms that were established during the last 50 years. The social …