Toxicology of deoxynivalenol and its acetylated and modified forms
D Payros, I Alassane-Kpembi, A Pierron, N Loiseau… - Archives of …, 2016 - Springer
Mycotoxins are the most frequently occurring natural contaminants in human and animal
diet. Among them, deoxynivalenol (DON), produced by Fusarium, is one of the most …
diet. Among them, deoxynivalenol (DON), produced by Fusarium, is one of the most …
From the gut to the brain: Journey and pathophysiological effects of the food-associated trichothecene mycotoxin deoxynivalenol
M Maresca - Toxins, 2013 - mdpi.com
Mycotoxins are fungal secondary metabolites contaminating food and causing toxicity to
animals and humans. Among the various mycotoxins found in crops used for food and feed …
animals and humans. Among the various mycotoxins found in crops used for food and feed …
A quick guide to small-molecule inhibitors of eukaryotic protein synthesis
SE Dmitriev, DO Vladimirov, KA Lashkevich - Biochemistry (Moscow), 2020 - Springer
Eukaryotic ribosome and cap-dependent translation are attractive targets in the antitumor,
antiviral, anti-inflammatory, and antiparasitic therapies. Currently, a broad array of small …
antiviral, anti-inflammatory, and antiparasitic therapies. Currently, a broad array of small …
Trichothecene toxicity in eukaryotes: Cellular and molecular mechanisms in plants and animals
C Arunachalam, FM Doohan - Toxicology letters, 2013 - Elsevier
Trichothecenes are sesquiterpenoid mycotoxins commonly found as contaminants in cereal
grains and are a major health and food safety concern due to their toxicity to humans and …
grains and are a major health and food safety concern due to their toxicity to humans and …
Trichothecenes: immunomodulatory effects, mechanisms, and anti-cancer potential
Q Wu, X Wang, E Nepovimova, A Miron, Q Liu… - Archives of …, 2017 - Springer
Paradoxically, trichothecenes have both immunosuppressive and immunostimulatory
effects. The underlying mechanisms have not been fully explored. Early studies show that …
effects. The underlying mechanisms have not been fully explored. Early studies show that …
Deoxynivalenol hijacks the pathway of Janus kinase 2/signal transducers and activators of transcription 3 (JAK2/STAT-3) to drive caspase-3-mediated apoptosis in …
Z Zhang, K Fan, J Meng, D Nie, Z Zhao… - Science of the Total …, 2023 - Elsevier
Deoxynivalenol (DON) can easily injure the intestinal tract, which represents the first barrier
against food contaminants. The intestinal toxicity induced by DON was mainly focused on …
against food contaminants. The intestinal toxicity induced by DON was mainly focused on …
Advances in deoxynivalenol toxicity mechanisms: the brain as a target
MS Bonnet, J Roux, L Mounien, M Dallaporta… - Toxins, 2012 - mdpi.com
Deoxynivalenol (DON), mainly produced by Fusarium fungi, and also commonly called
vomitoxin, is a trichothecene mycotoxin. It is one of the most abundant trichothecenes which …
vomitoxin, is a trichothecene mycotoxin. It is one of the most abundant trichothecenes which …
Diverse mycotoxin threats to safe food and feed cereals
RL Latham, JT Boyle, A Barbano… - Essays in …, 2023 - portlandpress.com
Toxigenic fungi, including Aspergillus and Fusarium species, contaminate our major cereal
crops with an array of harmful mycotoxins, which threaten the health of humans and farmed …
crops with an array of harmful mycotoxins, which threaten the health of humans and farmed …
Deoxynivalenol: Signaling pathways and human exposure risk assessment—An update
Z Wang, Q Wu, K Kuča, V Dohnal, Z Tian - Archives of toxicology, 2014 - Springer
Deoxynivalenol (DON) is a group B trichothecene and a common contaminant of crops
worldwide. This toxin is known to cause a spectrum of diseases in animals and humans …
worldwide. This toxin is known to cause a spectrum of diseases in animals and humans …
Chronic Exposure to the Fusarium Mycotoxin Deoxynivalenol: Impact on Performance, Immune Organ, and Intestinal Integrity of Slow-Growing Chickens
SS Chen, YH Li, MF Lin - Toxins, 2017 - mdpi.com
This study investigates the long-term effects of deoxynivalenol (DON) consumption on avian
growth performance, on the proliferation, apoptosis, and DNA damage of spleen cells, and …
growth performance, on the proliferation, apoptosis, and DNA damage of spleen cells, and …