Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

With the emergence of antibiotic resistance, the interest for antimicrobial agents has recently
increased again in public health. Copper was recognized in 2008 by the United States …

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is a feasible
technique to obtain either quantitative elemental data or spatially resolved imaging/mapping …

Gallic acid (GA) is a polyphenol natural compound found in many medicinal plant species,
including pomegranate rind (Punica granatum L.), and has been shown to have …

Metals such as Fe, Cu, Zn, and Mn are essential trace nutrients for all kingdoms of life,
including microbial pathogens and their hosts. During infection, the mammalian host …

The opportunistic fungal pathogen Candida albicans acquires essential metals from the
host, yet the host can sequester these micronutrients through a process known as nutritional …

Copper is an essential trace element participating in many vital biological processes,
however it becomes a toxic agent when in excess. Thus, precise and tight regulation of …

Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …

The Fenton-chemistry-generating properties of copper ions are considered a potent
phagolysosome defense against pathogenic microbes, yet our understanding of underlying …