Pathophysiology of cisplatin‐induced acute kidney injury
A Ozkok, CL Edelstein - BioMed research international, 2014 - Wiley Online Library
Cisplatin and other platinum derivatives are the most widely used chemotherapeutic agents
to treat solid tumors including ovarian, head and neck, and testicular germ cell tumors. A …
to treat solid tumors including ovarian, head and neck, and testicular germ cell tumors. A …
Biomarkers in acute kidney injury–pathophysiological basis and clinical performance
EV Schrezenmeier, J Barasch, K Budde… - Acta …, 2017 - Wiley Online Library
Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in
the recent past. These molecules can be detected in urine or blood and signify structural …
the recent past. These molecules can be detected in urine or blood and signify structural …
Biomarkers of drug-induced kidney toxicity
BR Griffin, S Faubel, CL Edelstein - Therapeutic drug monitoring, 2019 - journals.lww.com
Blood urea nitrogen and serum creatinine are imperfect markers of kidney function because
they are influenced by many renal and nonrenal factors independent of kidney function. A …
they are influenced by many renal and nonrenal factors independent of kidney function. A …
Biomarkers of acute kidney injury: the pathway from discovery to clinical adoption
K Kashani, W Cheungpasitporn… - Clinical Chemistry and …, 2017 - degruyter.com
Acute kidney injury (AKI) is a common complication of critical illnesses and has a significant
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …
Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes
VS Sabbisetti, SS Waikar, DJ Antoine… - Journal of the …, 2014 - journals.lww.com
Currently, no blood biomarker that specifically indicates injury to the proximal tubule of the
kidney has been identified. Kidney injury molecule-1 (KIM-1) is highly upregulated in …
kidney has been identified. Kidney injury molecule-1 (KIM-1) is highly upregulated in …
Biomarkers of renal function, which and when?
ME Wasung, LS Chawla, M Madero - Clinica chimica acta, 2015 - Elsevier
Purpose of the review Acute kidney injury (AKI) and chronic kidney disease (CKD) are
conditions that substantially increase morbidity and mortality. Although novel biomarkers are …
conditions that substantially increase morbidity and mortality. Although novel biomarkers are …
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
L Yang, TY Besschetnova, CR Brooks, JV Shah… - Nature medicine, 2010 - nature.com
Fibrosis is responsible for chronic progressive kidney failure, which is present in a large
number of adults in the developed world. It is increasingly appreciated that acute kidney …
number of adults in the developed world. It is increasingly appreciated that acute kidney …
Cardio-renal syndromes: report from the consensus conference of the acute dialysis quality initiative
A consensus conference on cardio-renal syndromes (CRS) was held in Venice Italy, in
September 2008 under the auspices of the Acute Dialysis Quality Initiative (ADQI). The …
September 2008 under the auspices of the Acute Dialysis Quality Initiative (ADQI). The …
Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis
M Haase, R Bellomo, P Devarajan… - American journal of …, 2009 - Elsevier
BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) appears to be a
promising biomarker for the early diagnosis of acute kidney injury (AKI); however, a wide …
promising biomarker for the early diagnosis of acute kidney injury (AKI); however, a wide …
Cardiorenal syndrome
The term cardiorenal syndrome (CRS) increasingly has been used without a consistent or
well-accepted definition. To include the vast array of interrelated derangements, and to …
well-accepted definition. To include the vast array of interrelated derangements, and to …