Cisplatin and other platinum derivatives are the most widely used chemotherapeutic agents
to treat solid tumors including ovarian, head and neck, and testicular germ cell tumors. A …

Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in
the recent past. These molecules can be detected in urine or blood and signify structural …

Blood urea nitrogen and serum creatinine are imperfect markers of kidney function because
they are influenced by many renal and nonrenal factors independent of kidney function. A …

Acute kidney injury (AKI) is a common complication of critical illnesses and has a significant
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …

Currently, no blood biomarker that specifically indicates injury to the proximal tubule of the
kidney has been identified. Kidney injury molecule-1 (KIM-1) is highly upregulated in …

Purpose of the review Acute kidney injury (AKI) and chronic kidney disease (CKD) are
conditions that substantially increase morbidity and mortality. Although novel biomarkers are …

Fibrosis is responsible for chronic progressive kidney failure, which is present in a large
number of adults in the developed world. It is increasingly appreciated that acute kidney …

A consensus conference on cardio-renal syndromes (CRS) was held in Venice Italy, in
September 2008 under the auspices of the Acute Dialysis Quality Initiative (ADQI). The …

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) appears to be a
promising biomarker for the early diagnosis of acute kidney injury (AKI); however, a wide …

The term cardiorenal syndrome (CRS) increasingly has been used without a consistent or
well-accepted definition. To include the vast array of interrelated derangements, and to …