Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Lactoferrin in a context of inflammation-induced pathology

ML Kruzel, M Zimecki, JK Actor - Frontiers in immunology, 2017 - frontiersin.org
Much progress has been achieved to elucidate the function of lactoferrin (LTF), an iron-
binding glycoprotein, in the milieu of immune functionality. This review represents a unique …

Iron and cancer risk—a systematic review and meta-analysis of the epidemiological evidence

A Fonseca-Nunes, P Jakszyn, A Agudo - Cancer epidemiology, biomarkers & …, 2014 - AACR
Iron has been suggested as a risk factor for different types of cancers mainly due to its
prooxidant activity, which can lead to oxidative DNA damage. Furthermore, subjects with …

Reversal of HO‐1 related cytoprotection with increased expression is due to reactive iron

DM Suttner, PA Dennery - The FASEB Journal, 1999 - Wiley Online Library
It is often postulated that the cytoprotective nature of heme oxygenase (HO‐1) explains the
inducible nature of this enzyme. However, the mechanisms by which protection occurs are …

Hydroxyl radicals from secondary organic aerosol decomposition in water

H Tong, AM Arangio, PSJ Lakey… - Atmospheric …, 2016 - acp.copernicus.org
We found that ambient and laboratory-generated secondary organic aerosols (SOA) form
substantial amounts of OH radicals upon interaction with liquid water, which can be …

Redox imbalance in the critically ill

JMC Gutteridge, J Mitchell - British Medical Bulletin, 1999 - academic.oup.com
The majority of deaths amongst critically ill patients requiring intensive care are attributable
to sepsis and its sequelae: septic shock, the systemic inflammatory response syndrome …

Albumin influences total plasma antioxidant capacity favorably in patients with acute lung injury

GJ Quinlan, S Mumby, GS Martin, GR Bernard… - Critical care …, 2004 - journals.lww.com
Albumin influences total plasma antioxidant capacity favorab... : Critical Care Medicine Albumin
influences total plasma antioxidant capacity favorably in patients with acute lung injury …

Iron metabolism in the lower respiratory tract

F Mateos, JH Brock, JL Pérez-Arellano - Thorax, 1998 - thorax.bmj.com
Background Iron is principally required for haemoglobin synthesis, and its uptake, utilisation
and storage are carefully regulated to ensure an adequate supply without excessive …

Roles of oxidants and redox signaling in the pathogenesis of acute respiratory distress syndrome

S Tasaka, F Amaya, S Hashimoto… - Antioxidants & redox …, 2008 - liebertpub.com
The acute respiratory distress syndrome (ARDS) is a disease process that is characterized
by diffuse inflammation in the lung parenchyma and resultant permeability edema. The …

Protein oxidation at the air-lung interface

FJ Kelly, IS Mudway - Amino acids, 2003 - Springer
Whilst performing its normal functions the lung is required to deal with a range of toxic
insults. Whether these are infectious agents, allergens or air pollutants they subject the lung …