Proteomics technologies for cancer liquid biopsies

Z Ding, N Wang, N Ji, ZS Chen - Molecular Cancer, 2022 - Springer
Alterations in DNAs could not reveal what happened in proteins. The accumulated
alterations of DNAs would change the manifestation of proteins. Therefore, as is the case in …

Electrochemical biosensors-sensor principles and architectures

D Grieshaber, R MacKenzie, J Vörös, E Reimhult - Sensors, 2008 - mdpi.com
Quantification of biological or biochemical processes are of utmost importance for medical,
biological and biotechnological applications. However, converting the biological information …

Nanomedicine—challenge and perspectives

K Riehemann, SW Schneider, TA Luger… - Angewandte Chemie …, 2009 - Wiley Online Library
The application of nanotechnology concepts to medicine joins two large cross‐disciplinary
fields with an unprecedented societal and economical potential arising from the natural …

Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps

T Guo, P Kouvonen, CC Koh, LC Gillet, WE Wolski… - Nature medicine, 2015 - nature.com
Clinical specimens are each inherently unique, limited and nonrenewable. Small samples
such as tissue biopsies are often completely consumed after a limited number of analyses …

Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins

L Anderson, CL Hunter - Molecular & Cellular Proteomics, 2006 - ASBMB
Quantitative LC-MS/MS assays were designed for tryptic peptides representing 53 high and
medium abundance proteins in human plasma using a multiplexed multiple reaction …

Biosensors for cancer markers diagnosis

IE Tothill - Seminars in cell & developmental biology, 2009 - Elsevier
Point-of-care diagnostic devices present a viable option for the rapid and sensitive detection
and analysis of cancer markers. With the growing number of cancer cases being diagnosed …

[HTML][HTML] The properties of high-dimensional data spaces: implications for exploring gene and protein expression data

R Clarke, HW Ressom, A Wang, J Xuan, MC Liu… - Nature reviews …, 2008 - nature.com
High-throughput genomic and proteomic technologies are widely used in cancer research to
build better predictive models of diagnosis, prognosis and therapy, to identify and …

[HTML][HTML] Multiplexed protein measurement: technologies and applications of protein and antibody arrays

SF Kingsmore - Nature reviews Drug discovery, 2006 - nature.com
The ability to measure the abundance of many proteins precisely and simultaneously in
experimental samples is an important, recent advance for static and dynamic, as well as …

Selective covalent protein immobilization: strategies and applications

LS Wong, F Khan, J Micklefield - Chemical reviews, 2009 - ACS Publications
The development and applications of site-selective protein immobilization have undergone
significant advances in recent years. Notably the recent fusion of synthetic chemistry and …

[HTML][HTML] Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics

H Padinharayil, J Varghese, MC John, GK Rajanikant… - Genes & …, 2023 - Elsevier
Continuous revision of the histologic and stage-wise classification of lung cancer by the
World Health Organization (WHO) provides the foundation for therapeutic advances by …