Human fibrocytes are mesenchymal progenitors that exhibit mixed morphological and
molecular characteristics of hematopoietic stem cells, monocytes and fibroblasts. They likely …

Helicobacter pylori (H. pylori) is the main cause of chronic gastritis and a major risk factor for
gastric cancer. This pathogen has also been considered a potential trigger of gastric …

Background: Systemic sclerosis is an immune-mediated rheumatic disease characterized by
vascular abnormalities, tissue fibrosis and autoimmune phenomena. Summary: Renal …

Systemic sclerosis (SSc) is a connective tissue disease secondary to three cardinal
pathological features: immune-system alterations, diffuse microangiopathy, and fibrosis …

Generalized vitiligo is an acquired disorder in which patches of depigmented skin, overlying
hair and oral mucosa result from progressive autoimmune loss of melanocytes from the …

Scleroderma renal crisis (SRC) is an infrequent but serious complication of systemic
sclerosis (SSc). It is associated with increased vascular permeability, activation of …

Transforming growth factor-β (TGF-β) plays a critical role in the development of tissue
fibrosis. Its expression is consistently elevated in affected organs and correlates with …

In this study, we aim to investigate retinal thickness (RT) and superficial vascular density
(SVD) differences between patients with systemic sclerosis (SSc) and healthy controls (HCs) …

MicroRNAs (miRNAs) are well-known candidates for modulating the dysregulated signaling
pathways during fibrosis. In this study, we investigated the expression pattern of 16 miRNAs …

OBJECTIVE: To evaluate the frequency and characteristics of ocular manifestations in
outpatients with systemic sclerosis. METHODS: In this cross-sectional study, 45 patients with …