[PDF][PDF] Galleria mellonella–intracellular bacteria pathogen infection models: the ins and outs

M Asai, Y Li, SM Newton, BD Robertson… - FEMS Microbiology …, 2023 - academic.oup.com
Galleria mellonella (greater wax moth) larvae are used widely as surrogate infectious
disease models, due to ease of use and the presence of an innate immune system …

Higenamine in plants as a source of unintentional doping

V Rangelov Kozhuharov, K Ivanov, S Ivanova - Plants, 2022 - mdpi.com
Background: Higenamine is a β2 agonist of plant origin. The compound has been included
in WADA's prohibited list since 2017. Higenamine may be detected in different plants and …

UtilisingGalleria mellonella larvae for studying in vivo activity of conventional and novel antimicrobial agents

M Piatek, G Sheehan, K Kavanagh - Pathogens and Disease, 2020 - academic.oup.com
The immune response of insects displays many structural and functional similarities to the
innate immune response of mammals. As a result of these conserved features, insects may …

Galleria mellonella - a novel infection model for the Mycobacterium tuberculosis complex

Y Li, J Spiropoulos, W Cooley, JS Khara, CA Gladstone… - Virulence, 2018 - Taylor & Francis
Animal models have long been used in tuberculosis research to understand disease
pathogenesis and to evaluate novel vaccine candidates and anti-mycobacterial drugs …

Enhanced therapeutic efficacy of biogenic nanosilver-conjugated thymol: In vitro and in vivo evaluation against emerging multi-drug resistant microbes

VP Ram, J Yasur, P Abishad, C Ramesh… - Journal of Drug Delivery …, 2023 - Elsevier
Phytochemicals and nanoparticles (NPs) despite having strong antibacterial activity, their
limited stability and safety prevent their widespread biomedical and environmental …

Higenamine mitigates interleukin-1β-induced human nucleus pulposus cell apoptosis by ROS-mediated PI3K/Akt signaling

X Zhu, S Liu, Z Cao, L Yang, F Lu, Y Li, L Hu… - Molecular and Cellular …, 2021 - Springer
Intervertebral disc degeneration (IDD) is a natural problem linked to the inflammation.
Higenamine exerts multiple pharmacological properties in inflammation-related disorders …

Synthesis and Antimicrobial Activity of Novel Piperidinyl Tetrahydrothieno[2,3-c]isoquinolines and Related Heterocycles

RM Zaki, AM Kamal El-Dean, SM Radwan… - ACS …, 2019 - ACS Publications
A novel series of 1-amino-2-substituted-5-piperidinyl-6, 7, 8, 9-tertahydrothieno [2, 3-c]
isoquinolines (4a–e) was synthesized upon treatment of 4-cyano-1-piperidinyl-5, 6, 7, 8 …

Galleria mellonella experimental model for bat fungal pathogen Pseudogymnoascus destructans and human fungal pathogen Pseudogymnoascus pannorum

BB Fuchs, S Chaturvedi, RD Rossoni, PP De Barros… - Virulence, 2018 - Taylor & Francis
Laboratory investigations of the pathogenesis of Pseudogymnoascus destructans, the fungal
causal agent of bat White Nose Syndrome (WNS), presents unique challenges due to its …

[PDF][PDF] Higenamine in Plants as a Source of Unintentional Doping. Plants. 2022; 11: 354

V Rangelov Kozhuharov, K Ivanov, S Ivanova - 2022 - researchgate.net
Background: Higenamine is a β2 agonist of plant origin. The compound has been included
in WADA's prohibited list since 2017. Higenamine may be detected in different plants and …

Morphological and anatomical diagnostic features of Aristolochia clematitis L. herb.

I Suina, O Yakovleva, I Terninko… - Thai Journal of …, 2020 - tjps.pharm.chula.ac.th
Diagnostic features of Aristolochia clematitis L. herb were established as an obligatory
element for standardization of medicinal plant raw materials. They are as follows: stems are …