This review summarises current understanding of how bone is sculpted through adaptive
processes, designed to meet the mechanical challenges it faces in everyday life and athletic …

Osteoporosis is becoming an increasingly important public health issue, and effective
treatments to prevent fragility fractures are available. Osteoporosis imaging is of critical …

The primary goal of this study was to assess peripheral bone microarchitecture and strength
in postmenopausal women with type 2 diabetes with fragility fractures (DMFx) and to …

Osteoporosis is associated with increased fragility of bone and a subsequent increased risk
of fracture. The diagnosis of osteoporosis is intimately linked with the imaging and …

Understanding how bones are innately designed, robustly developed and delicately
maintained through intricate anatomical features and physiological processes across the …

Context: Cross-sectional epidemiological studies have found that patients with type 2
diabetes mellitus (T2DM) have a higher incidence of certain fragility fractures despite normal …

Quantitative cortical microarchitectural end points are important for understanding structure–
function relations in the context of fracture risk and therapeutic efficacy. This technique study …

Background The role of bone structure, one component of bone quality, has emerged as a
contributor to bone strength. The application of high-resolution imaging in evaluating bone …

Bone structure is an integral determinant of bone strength. The availability of high resolution
peripheral quantitative computed tomography (HR-pQCT) has made it possible to measure …

The treatment of sizeable segmental bone defects remains a challenge encountered by
surgeons. In addition to bone transplantation, porous scaffolds have become a common …