Anhedonia, or markedly diminished interest or pleasure, is a hallmark symptom of major
depression, schizophrenia and other neuropsychiatric disorders. Over the past three …

Despite numerous studies on the neurobiology of depression, the etiological and
pathophysiological mechanisms of this disorder remain poorly understood. A large number …

Anhedonia, the lack of pleasure, has been shown to be a critical feature of a range of
psychiatric disorders. Yet, it is currently measured primarily through subjective self-reports …

The aim of this review was to develop an empirically supported cognitive behavioural model
of compulsive exercise within the context of the eating disorders. A systematic review of the …

In this paper we argue that compulsive overeating has compelling similarities to
conventional drug addiction. Our case is based on their comparable clinical features, the …

This focussed narrative review examines neurobiological and psychophysiological evidence
supporting a role for altered reward processes in the development and maintenance of …

A network of interconnected brain regions, including orbitofrontal, ventral striatal, amygdala,
and midbrain areas, has been widely implicated in a number of aspects of food reward …

Studies have shown increased risk taking in healthy individuals after low-frequency
repetitive transcranial magnetic stimulation, known to transiently suppress cortical …

Sensitivity to reward (STR)—a personality trait firmly rooted in the neurobiology of the
mesolimbic dopamine system—has been strongly implicated in the risk for addiction. This …

BACKGROUND: Anhedonia, the inability to experience pleasure, is a major endophenotype
of depression. In addition to this, it is an important clinical feature of schizophrenia and …