Peptidoglycan synthesis drives a single population of septal cell wall synthases during division in Bacillus subtilis

KD Whitley, J Grimshaw, DM Roberts, E Karinou… - Nature …, 2024 - nature.com
Bacterial cell division requires septal peptidoglycan (sPG) synthesis by the divisome
complex. Treadmilling of the essential tubulin homologue FtsZ has been implicated in septal …

Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody

J Fujita, H Amesaka, T Yoshizawa, K Hibino… - Nature …, 2023 - nature.com
FtsZ polymerizes into protofilaments to form the Z-ring that acts as a scaffold for accessory
proteins during cell division. Structures of FtsZ have been previously solved, but detailed …

Survival of E. coli O157: H7, Salmonella Typhimurium, HAdV2 and MNV-1 in river water under dark conditions and varying storage temperatures

EMMEM Ibrahim, MA El-Liethy, ALK Abia… - Science of the total …, 2019 - Elsevier
The ability of Escherichia coli O157: H7, Salmonella enterica serovar Typhimurium, Human
adenovirus serotype 2 (HAdV2) and Murine Norovirus 1 (MNV-1) to survive in river water at …

A one-track model for spatiotemporal coordination of Bacillus subtilis septal cell wall synthesis

KD Whitley, J Grimshaw, DM Roberts, E Karinou… - bioRxiv, 2023 - biorxiv.org
Bacterial cell division requires synthesis of a septal peptidoglycan (sPG) wall across the
middle of the cell. This is accomplished by the divisome synthesis complex in coordination …

Behaviors of individual microtubules and microtubule populations relative to critical concentrations: dynamic instability occurs when critical concentrations are driven …

EM Jonasson, AJ Mauro, C Li, EC Labuz… - Molecular biology of …, 2020 - Am Soc Cell Biol
The concept of critical concentration (CC) is central to understanding the behavior of
microtubules (MTs) and other cytoskeletal polymers. Traditionally, these polymers are …

Glutamate Dehydrogenase (GdhA) of Streptococcus pneumoniae is required for high temperature adaptation

O Gazioglu, BO Kareem, M Afzal, S Shafeeq… - Infection and …, 2021 - Am Soc Microbiol
During its progression from the nasopharynx to other sterile and nonsterile niches of its
human host, Streptococcus pneumoniae must cope with changes in temperature. We …

Gene knockout revealed the role of gene feoA in cell growth and division of Lactobacillus delbrueckii subsp. bulgaricus

X Han, Y Tu, H Wu, L Zhang, S Zhao - Archives of Microbiology, 2021 - Springer
Gene feoA plays an important role in cell growth because of its function of transport Fe2+
which is a necessary element for cells. In this study, the recombinant plasmid pUC19-feoA …

M. jannaschii FtsZ, a key protein in bacterial cell division, is inactivated by peroxyl radical-mediated methionine oxidation

JS Reyes, E Fuentes-Lemus, A Aspee… - Free Radical Biology …, 2021 - Elsevier
Oxidation and inactivation of FtsZ is of interest due to the key role of this protein in bacterial
cell division. In the present work, we studied peroxyl radical (from AAPH, 2, 2′-azobis (2 …

[PDF][PDF] Subcellular Systems Observe Onsager Reciprocity

A Horowitz - 2024 - assets-eu.researchsquare.com
The motivation for this study is an emerging conceptual shift from the mechanistic dogma
whereby discrete molecular machines perform strictly defined roles to focusing on the …

Leveraging Thermodynamic Reciprocity to Quantify Cellular Dynamics

A Horowitz - 2024 - researchsquare.com
The complexity of prokaryotic and, exceedingly, of eukaryotic cells, challenges the
implementation of methodologies to determine causality and quantify intracellular dynamics …