Loss of B‐cell lymphoma 2 immunohistochemical expression in endometrial hyperplasia: a specific marker of precancer and novel indication for treatment: a …

A Travaglino, A Raffone, G Saccone… - Acta Obstetricia et …, 2018 - Wiley Online Library
Introduction Endometrial hyperplasia is differentiated into benign or premalignant. Two
histological classifications are used for this purpose: World Health Organization (WHO) …

Immunocytochemical assessment of mitotic activity with an antibody to phosphorylated histone H3 in the macaque and human endometrium

RM Brenner, OD Slayden, WH Rodgers… - Human …, 2003 - academic.oup.com
BACKGROUND: Determination of the mitotic index in sections of endometrium stained with
haematoxylin and eosin (H&E) is difficult and time‐consuming. We assessed the value of …

Immunohistochemical expression of PTEN in normal, hyperplastic and malignant endometrium and its correlation with hormone receptors, bcl-2, bax, and apoptotic …

N Kapucuoglu, F Aktepe, H Kaya, S Bircan… - … -Research and Practice, 2007 - Elsevier
PTEN is a tumor supressor gene that is frequently mutated in type I endometrioid
endometrial carcinomas (EECs), and is involved in the control of cell proliferation …

Bcl‐2, iNOS, p53 and PCNA expression in normal, disordered proliferative, hyperplastic and malignant endometrium

L Cinel, A Polat, Ö Aydin, D Düşmez… - Pathology …, 2002 - Wiley Online Library
We attempted to determine Bcl‐2, inducible nitric oxide synthase (iNOS), p53 and
proliferating cell nuclear antigen (PCNA) expression, and the relationships between them, in …

Современные представления об этиологии и патогенезе гиперпластических процессов эндометрия

ВМ Пашков, ВА Лебедев, МВ Коваленко - … гинекологии, акушерства и …, 2006 - elibrary.ru
Представлены современные положения этиологии и патогенеза гиперпластических
процессов эндометрия. Освещены морфологическая характеристика эндометрия в …

[PDF][PDF] Диагностическая и прогностическая значимость оценки пролиферативной активности клеточных популяций эндометрия при гиперпластических и …

ЕВ Махина, АК Пичигина… - …, 2014 - s.fundamental-research.ru
Исследование пролиферативной активности клеток имеет большое значение для
установления диагноза и прогноза широкого спектра патологических процессов …

Экспрессия генов, регулирующих апоптоз, при разных типах гиперплазии эндометрия и эндометриоидной карциноме

ГЕ ЧЕРНУХА, МР ДУМАНОВСКАЯ… - Акушерство и …, 2013 - elibrary.ru
Цель исследования: определение клинической значимости экспрессии мРНК генов,
участвующих в процессах апоптоза, и гена-супрессора опухолевого роста PTEN при …

Adrenomedullin, Bcl‐2 and microvessel density in normal, hyperplastic and neoplastic endometrium

O Nunobiki, M Nakamura, E Taniguchi… - Pathology …, 2009 - Wiley Online Library
Adrenomedullin (ADM) is a multifunctional 52‐amino acid peptide involved in numerous
physiological and pathological processes, including angiogenesis, growth regulation …

Genetic alterations in endometrial hyperplasia and cancer

G Fabjani, E Kucera, E Schuster, M Minai-Pour… - Cancer letters, 2002 - Elsevier
Putative precursors of endometrial cancer such as complex endometrial hyperplasia with
atypia have been described to be monoclonal and considered to be genetically related. In …

Bcl-2 exerts a pRb-mediated cell cycle inhibitory function in HEC1B endometrial carcinoma cells

E Crescenzi, G Palumbo - Gynecologic oncology, 2001 - Elsevier
Objective. In various human tumors the expression of Bcl-2 appears to vary significantly
during the transformation process. Indeed, in several glandular systems, Bcl-2 levels appear …