[HTML][HTML] Homeodomain proteins: an update
TR Bürglin, M Affolter - Chromosoma, 2016 - Springer
Here, we provide an update of our review on homeobox genes that we wrote together with
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …
Insertion sequences
J Mahillon, M Chandler - Microbiology and molecular biology …, 1998 - Am Soc Microbiol
Insertion sequences (ISs) constitute an important component of most bacterial genomes.
Over 500 individual ISs have been described in the literature to date, and many more are …
Over 500 individual ISs have been described in the literature to date, and many more are …
[HTML][HTML] Sleeping Beauty–engineered CAR T cells achieve antileukemic activity without severe toxicities
BACKGROUND Chimeric antigen receptor (CAR) T cell immunotherapy has resulted in
complete remission (CR) and durable response in highly refractory patients. However …
complete remission (CR) and durable response in highly refractory patients. However …
[HTML][HTML] Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
Members of the Tc1/mariner superfamily of transposons isolated from fish appear to be
transpositionally inactive due to the accumulation of mutations. Molecular phylogenetic data …
transpositionally inactive due to the accumulation of mutations. Molecular phylogenetic data …
[HTML][HTML] Contemporary Transposon Tools: A Review and Guide through Mechanisms and Applications of Sleeping Beauty, piggyBac and Tol2 for Genome …
N Sandoval-Villegas, W Nurieva, M Amberger… - International journal of …, 2021 - mdpi.com
Transposons are mobile genetic elements evolved to execute highly efficient integration of
their genes into the genomes of their host cells. These natural DNA transfer vehicles have …
their genes into the genomes of their host cells. These natural DNA transfer vehicles have …
Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage
K Kawakami, A Shima… - Proceedings of the …, 2000 - National Acad Sciences
The Tol2 element of the medaka fish Oryzias latipes belongs to the hAT family of
transposons (hobo/Ac/Tam3). We report here identification of a functional transposase of …
transposons (hobo/Ac/Tam3). We report here identification of a functional transposase of …
Resident aliens: the Tc1/mariner superfamily of transposable elements
Transgenic technology is currently applied to several animal species of agricultural or
medical importance, such as fish, cattle, mosquitos and parasitic worms. However, the …
medical importance, such as fish, cattle, mosquitos and parasitic worms. However, the …
Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates
Sleeping Beauty (SB), a member of the Tc1/mariner superfamily of transposable elements, is
the only active DNA-based transposon system of vertebrate origin that is available for …
the only active DNA-based transposon system of vertebrate origin that is available for …
[HTML][HTML] Gene transfer into genomes of human cells by the sleeping beauty transposon system
Abstract The Sleeping Beauty (SB) transposon system, derived from teleost fish sequences,
is extremely effective at delivering DNA to vertebrate genomes, including those of humans …
is extremely effective at delivering DNA to vertebrate genomes, including those of humans …
A highly soluble Sleeping Beauty transposase improves control of gene insertion
I Querques, A Mades, C Zuliani, C Miskey, M Alb… - Nature …, 2019 - nature.com
Abstract The Sleeping Beauty (SB) transposon system is an efficient non-viral gene transfer
tool in mammalian cells, but its broad use has been hampered by uncontrolled transposase …
tool in mammalian cells, but its broad use has been hampered by uncontrolled transposase …