Background There are few available antidepressants for pediatric Major Depressive
Disorder (MDD). The objective of this systematic review and meta-analysis was to review …

Introduction Pharmacotherapy of depression is characterized by the delayed onset of action,
chronic treatment requirements, and insufficient effectiveness. Ketamine, with its rapid action …

Background Randomized controlled clinical trials have shown vortioxetine to be efficacious
and well tolerated for the treatment of major depressive disorder (MDD). The Real-Life …

Background: Major depressive disorder (MDD) and generalized anxiety disorder (GAD) are
frequently comorbid. Aims: To assess the effectiveness of vortioxetine in patients with MDD …

Objective: To compare the efficacy of vortioxetine and the serotonin-norepinephrine
reuptake inhibitor (SNRI) desvenlafaxine in patients with major depressive disorder (MDD) …

Background Patients with major depressive disorder (MDD) often experience comorbid
anxiety symptoms. Vortioxetine has demonstrated efficacy in treating anxiety symptoms in …

Background Vortioxetine has demonstrated procognitive effects in patients with major
depressive disorder (MDD). We assessed the effectiveness and safety of vortioxetine in a …

BackgroundVortioxetine has demonstrated dose-dependent efficacy in patients with major
depressive disorder (MDD), with the greatest effect observed with vortioxetine 20 mg/day …

Background The multimodal antidepressant vortioxetine is effective in reducing somatic
symptoms in patients with major depressive disorder (MDD), but little is known about its …

Background Functional recovery is an important treatment goal in major depressive disorder
(MDD). This study assessed the real-world effectiveness of vortioxetine in patients with …