Histone acetyltransferases
▪ Abstract Transcriptional regulation in eukaryotes occurs within a chromatin setting and is
strongly influenced by nucleosomal barriers imposed by histone proteins. Among the well …
strongly influenced by nucleosomal barriers imposed by histone proteins. Among the well …
Functions of site-specific histone acetylation and deacetylation
MD Shahbazian, M Grunstein - Annu. Rev. Biochem., 2007 - annualreviews.org
Histone acetylation regulates many cellular processes, and specific acetylation marks, either
singly or in combination, produce distinct outcomes. For example, the acetylation pattern on …
singly or in combination, produce distinct outcomes. For example, the acetylation pattern on …
Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
RD Kornberg, Y Lorch - Cell, 1999 - cell.com
Roger D. Kornberg* and Yahli Lorch Department of Structural Biology Stanford University
School of Medicine Stanford, California 94305 model building and other predictive structural …
School of Medicine Stanford, California 94305 model building and other predictive structural …
Acetylation of histones and transcription-related factors
DE Sterner, SL Berger - Microbiology and molecular biology …, 2000 - Am Soc Microbiol
The state of chromatin (the packaging of DNA in eukaryotes) has long been recognized to
have major effects on levels of gene expression, and numerous chromatin-altering …
have major effects on levels of gene expression, and numerous chromatin-altering …
Histone acetylation and transcriptional regulatory mechanisms
K Struhl - Genes & development, 1998 - genesdev.cshlp.org
More than 30 years ago, Vincent Allfrey proposed that histone acetylation was associated
with transcriptional activity in eukaryotic cells (Allfrey et al. 1964; Pogo et al. 1966) …
with transcriptional activity in eukaryotic cells (Allfrey et al. 1964; Pogo et al. 1966) …
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
Y Zhang, D Reinberg - Genes & development, 2001 - genesdev.cshlp.org
In this review, we discuss recent advances made on histone methylation and its diverse
functions in regulating gene expression. Methylation of histone polypeptides might be static …
functions in regulating gene expression. Methylation of histone polypeptides might be static …
Roles of histone acetyltransferases and deacetylases in gene regulation
MH Kuo, CD Allis - Bioessays, 1998 - Wiley Online Library
Acetylation of internal lysine residues of core histone N‐terminal domains has been found
correlatively associated with transcriptional activation in eukaryotes for more than three …
correlatively associated with transcriptional activation in eukaryotes for more than three …
[HTML][HTML] Genome-wide map of nucleosome acetylation and methylation in yeast
Eukaryotic genomes are packaged into nucleosomes whose position and chemical
modification state can profoundly influence regulation of gene expression. We profiled …
modification state can profoundly influence regulation of gene expression. We profiled …
Histone acetylation and an epigenetic code
BM Turner - Bioessays, 2000 - Wiley Online Library
The enzyme‐catalyzed acetylation of the N‐terminal tail domains of core histones provides a
rich potential source of epigenetic information. This may be used both to mediate transient …
rich potential source of epigenetic information. This may be used both to mediate transient …
Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation
VM Richon, TW Sandhoff… - Proceedings of the …, 2000 - National Acad Sciences
Histone deacetylases (HDACs) catalyze the removal of acetyl groups on the amino-terminal
lysine residues of core nucleosomal histones. This activity is associated generally with …
lysine residues of core nucleosomal histones. This activity is associated generally with …