Dear Editor, In the nematode Caenorhabditis elegans, the systemic RNA interference
defective protein 1 (SID-1) plays a crucial role in systemic RNA interference (RNAi) by …

The SID1 transmembrane family, member 2, namely, Sidt2, is a highly glycosylated
multichannel lysosomal transmembrane protein, but its specific physiological function …

RNA uptake by cells is critical for RNA-mediated gene interference (RNAi) and RNA-based
therapeutics. In Caenorhabditis elegans, RNAi is systemic as a result of SID-1-mediated …

Genetic associations for lipid traits have identified hundreds of variants with clear differences
across European, Asian and African studies. Based on a sub-Saharan-African GWAS for …

Previous studies have reported that the SIDT2 and ABCA1 genes are involved in lipid
metabolism. We aimed to analyze the association—the gene x gene interaction between …

The mammalian SID-1 transmembrane family members, SIDT1 and SIDT2, are multi-pass
transmembrane proteins that mediate the cellular uptake and intracellular trafficking of …

Plasma lipid levels are risk factors for cardiovascular disease, a leading cause of death
worldwide. While many studies have been conducted in genetic variation underlying lipid …

While cholesterol is essential, a high level of cholesterol is associated with the risk of
cardiovascular diseases. Genome-wide association studies (GWASs) have proven …

A number of genome-wide association studies (GWASs) have identified several genetic
determinants of plasma lipids in European populations, in which analytical approaches have …

The Mexican population has one of the highest prevalences of metabolic syndrome (MetS)
worldwide. The aim of this study was to investigate the association of single-nucleotide …