Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

The demonstration of metabolically active brown adipose tissue (BAT) in humans primarily
using positron emission tomography coupled to computed tomography (PET/CT) with the …

Human brown adipose tissue (BAT) can be activated to increase glucose uptake and energy
expenditure, making it a potential target for treating obesity and metabolic disease. Data on …

Acute psychological stress has long been known to decrease host fitness to inflammation in
a wide variety of diseases, but how this occurs is incompletely understood. Using mouse …

Major burns provoke a profound stress response, which is unrivalled in terms of its
magnitude and duration. Evidence suggests that the pathophysiological stress response to …

Obesity surgery remains the most effective treatment for obesity and its complications.
Weight loss was initially attributed to decreased energy absorption from the gut but has …

Burn is an under-appreciated trauma that is associated with unacceptably high morbidity
and mortality. Although the survival rate after devastating burn injuries has continued to …

The association of brown adipose tissue (BAT) and body fat distribution and their combined
effects on metabolic health in humans remains unknown. Here, we retrospectively identify …

The G protein–coupled receptor 84 (GPR84), a medium-chain fatty acid receptor, has
garnered attention because of its potential involvement in a range of metabolic conditions …

Brown adipose tissue is a thermogenic organ that dissipates chemical energy as heat to
protect animals against hypothermia and to counteract metabolic disease. However, the …