Diagnosis and treatment of pulmonary arterial hypertension: a review

NF Ruopp, BA Cockrill - Jama, 2022 - jamanetwork.com
Importance Pulmonary arterial hypertension (PAH) is a subtype of pulmonary hypertension
(PH), characterized by pulmonary arterial remodeling. The prevalence of PAH is …

Updated clinical classification of pulmonary hypertension

G Simonneau, MA Gatzoulis, I Adatia… - Journal of the American …, 2013 - jacc.org
In 1998, a clinical classification of pulmonary hypertension (PH) was established,
categorizing PH into groups which share similar pathological and hemodynamic …

Definitions and diagnosis of pulmonary hypertension

MM Hoeper, HJ Bogaard, R Condliffe, R Frantz… - Journal of the American …, 2013 - jacc.org
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure≥ 25 mm Hg
at rest, measured during right heart catheterization. There is still insufficient evidence to add …

Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European …

N Galiè, MM Hoeper, M Humbert, A Torbicki… - European heart …, 2009 - academic.oup.com
Thus, the task of writing Guidelines or Expert Consensus documents covers not only the
integration of the most recent research, but also the creation of educational tools and …

A novel channelopathy in pulmonary arterial hypertension

L Ma, D Roman-Campos, ED Austin… - … England Journal of …, 2013 - Mass Medical Soc
Background Pulmonary arterial hypertension is a devastating disease with high mortality.
Familial cases of pulmonary arterial hypertension are usually characterized by autosomal …

Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era

M Humbert, O Sitbon, A Chaouat, M Bertocchi… - Circulation, 2010 - Am Heart Assoc
Background—Novel therapies have recently become available for pulmonary arterial
hypertension. We conducted a study to characterize mortality in a multicenter prospective …

[HTML][HTML] Mechanisms of disease: pulmonary arterial hypertension

RT Schermuly, HA Ghofrani, MR Wilkins… - Nature Reviews …, 2011 - nature.com
Our understanding of, and approach to, pulmonary arterial hypertension has undergone a
paradigm shift in the past decade. Once a condition thought to be dominated by increased …

EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension

M Eyries, D Montani, B Girerd, C Perret, A Leroy… - Nature …, 2014 - nature.com
Pulmonary veno-occlusive disease (PVOD) is a rare and devastating cause of pulmonary
hypertension that is characterized histologically by widespread fibrous intimal proliferation of …

Advances in therapeutic interventions for patients with pulmonary arterial hypertension

M Humbert, EMT Lau, D Montani, X Jaïs, O Sitbon… - Circulation, 2014 - Am Heart Assoc
Pulmonary arterial hypertension (PAH) is a disease characterized by progressive
remodeling of the distal pulmonary arteries, resulting in the loss of vascular cross-sectional …

Sex and gender differences in lung disease

P Silveyra, N Fuentes, DE Rodriguez Bauza - Lung Inflammation in Health …, 2021 - Springer
Sex differences in the anatomy and physiology of the respiratory system have been widely
reported. These intrinsic sex differences have also been shown to modulate the …