Breast cancer (BC) is a common cancer all over the world that affects women. BC is one of
the leading causes of cancer mortality in women, which today has decreased with the …

Estrogen receptor alpha (ER) is a transcriptional regulator that controls the expression of
genes related to cellular proliferation and differentiation in normal mammary tissue …

The glucocorticoid receptor (GR) is phosphorylated at multiple sites within its N terminus
(S203, S211, S226), yet the role of phosphorylation in receptor function is not understood …

Estrogens promote cell proliferation and metastases in several human cancers. Here, we
describe a different action of estrogens likely to contribute to tumor development-blocking …

Transcriptional regulation of ESR1, the gene that encodes for estrogen receptor α (ER), is
critical for regulating the downstream effects of the estrogen signaling pathway in breast …

Estrogen receptor-alpha (ERα) is an important biomarker used to classify and direct therapy
decisions in breast cancer (BC). Both ERα protein and its transcript, ESR1, are used to …

Gene expression results from the coordinated actions of transcription factor proteins and
coregulators. Estrogen receptor alpha (ERα) is a ligand-activated transcription factor that …

Most of the studies on advanced glycation end products (AGE) have been carried out with
uncharacterized mixtures of AGE, so the observed effects cannot be linked to defined …

Recurrent estrogen receptor α (ERα)-positive breast and ovarian cancers are often therapy
resistant. Using screening and functional validation, we identified BHPI, a potent …

More than 70% of all breast cancer cases are estrogen receptor alpha-positive (ERα). ERα
is a member of the nuclear receptor family, and its activity is implicated in the gene …