Kinesins are a family of molecular motors that travel unidirectionally along microtubule
tracks to fulfil their many roles in intracellular transport or cell division. Over the past few …

Accurate chromosome segregation in mitosis is crucial to maintain a diploid chromosome
number. A majority of cancer cells are aneuploid and chromosomally unstable, ie they tend …

This article features online supplementary material. In this article, we propose a
computationally efficient approach—space (Sparse PArtial Correlation Estimation)—for …

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is the
fourth-leading cause of cancer-related deaths worldwide. HCC is refractory to many …

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Intense
efforts have been made to elucidate the pathogeny, but the molecular mechanisms of HCC …

Abstract Background Kinesin superfamily (KIFs) has a long-reported significant influence on
the initiation, development, and progress of breast cancer. However, the prognostic value of …

Breast cancer pathobiology is known to be influenced by the differential expression of a
group of proteins called the kinesin superfamily (KIFs), which is instrumental in the …

Although the associations of p53 dysfunction, p53 interaction networks and oncogenesis
have been widely explored, a systematic analysis of TP53 mutations and its related …

Triple negative breast cancer (TNBC) has a poor outcome due to the lack of beneficial
therapeutic targets. To clarify the molecular mechanisms involved in the carcinogenesis of …

Background The kinesin-13 family member 2C (KIF2C) is a versatile protein participating in
many biological processes. KIF2C is frequently up-regulated in multiple types of cancer and …