Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation

R Wild, J Kowal, J Eyring, EM Ngwa, M Aebi… - Science, 2018 - science.org
Oligosaccharyltransferase (OST) is an essential membrane protein complex in the
endoplasmic reticulum, where it transfers an oligosaccharide from a dolichol-pyrophosphate …

The atomic structure of a eukaryotic oligosaccharyltransferase complex

L Bai, T Wang, G Zhao, A Kovach, H Li - Nature, 2018 - nature.com
N-glycosylation is a ubiquitous modification of eukaryotic secretory and membrane-bound
proteins; about 90% of glycoproteins are N-glycosylated. The reaction is catalysed by an …

Murine astrotactins 1 and 2 have a similar membrane topology and mature via endoproteolytic cleavage catalyzed by a signal peptidase

P Lara, Å Tellgren-Roth, H Behesti, Z Horn… - Journal of Biological …, 2019 - ASBMB
Astrotactin 1 (Astn1) and Astn2 are membrane proteins that function in glial-guided
migration, receptor trafficking, and synaptic plasticity in the brain as well as in planar polarity …

AlignMe: an update of the web server for alignment of membrane protein sequences

R Staritzbichler, E Yaklich, E Sarti, N Ristic… - Nucleic Acids …, 2022 - academic.oup.com
The AlignMe web server is dedicated to accurately aligning sequences of membrane
proteins, a particularly challenging task due to the strong evolutionary divergence and the …

[HTML][HTML] Current Progress in Cancer Immunotherapies Using Small Molecules Targeting PD-L1 Stability

M Leung, A Pipchuk, X Yang - OBM Genetics, 2021 - lidsen.com
PD-L1 is an immune checkpoint protein that is frequently overexpressed by the cells in the
tumor microenvironment. PD-L1 binds to PD-1 present on the activated antitumor T-cells …

[PDF][PDF] Patricia Lara1, Åsa Tellgren-Roth1, Hourinaz Behesti2, Zachi Horn2, Nina Schiller1, Karl Enquist1, Malin Cammenberg1, Amanda Liljenström1, Mary E …

G von Heijne, IM Nilsson - researchgate.net
ABSTRACT Astrotactins 1 and 2 (Astn1, Astn2) are membrane proteins that function in glial-
guided migration, receptor trafficking and synaptic plasticity in brain, as well as in planar …

Astrotactins 1 and 2 have similar membrane topology and mature via endoproteolytic cleavage catalyzed by signal peptidase

P Lara, Å Tellgren-Roth, H Behesti, Z Horn, N Schiller… - bioRxiv, 2018 - biorxiv.org
Astrotactins 1 (Astn1) and Astn2 are membrane proteins that function in glial-guided
migration, receptor trafficking and synaptic plasticity in the brain, as well as in planar polarity …

[引用][C] Genomic, genetic, and mass spectrometry glycoproteomic investigations of the roles of Oligosaccharyltransferase subunits in N-glycosylation in yeast

C Zhou - 2024 - espace.library.uq.edu.au
Protein glycosylation is one of the most important co-and post-translational modifications
(PTMs) in eukaryotic cells, which regulates protein folding, stability, and trafficking, and …