The toxicity of nanoparticles and their interaction with cells: an in vitro metabolomic perspective
Nowadays, nanomaterials (NMs) are widely present in daily life due to their significant
benefits, as demonstrated by their application in many fields such as biomedicine …
benefits, as demonstrated by their application in many fields such as biomedicine …
Machine learning-integrated omics for the risk and safety assessment of nanomaterials
With the advancement in nanotechnology, we are experiencing transformation in world
order with deep insemination of nanoproducts from basic necessities to advanced …
order with deep insemination of nanoproducts from basic necessities to advanced …
[HTML][HTML] Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic …
A Schaffert, I Karkossa, E Ueberham… - Environment …, 2022 - Elsevier
The obesity pandemic is presumed to be accelerated by endocrine disruptors such as
phthalate-plasticizers, which interfere with adipose tissue function. With the restriction of the …
phthalate-plasticizers, which interfere with adipose tissue function. With the restriction of the …
Progress in toxicogenomics to protect human health
Toxicogenomics measures molecular features, such as transcripts, proteins, metabolites and
epigenomic modifications, to understand and predict the toxicological effects of …
epigenomic modifications, to understand and predict the toxicological effects of …
[HTML][HTML] Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation
A Schaffert, L Krieg, J Weiner, R Schlichting… - Environment …, 2021 - Elsevier
Bisphenol A (BPA), which is used in a variety of consumer-related plastic products, was
reported to cause adverse effects, including disruption of adipocyte differentiation …
reported to cause adverse effects, including disruption of adipocyte differentiation …
The emerging plasticizer alternative DINCH and its metabolite MINCH induce oxidative stress and enhance inflammatory responses in human THP-1 macrophages
The use of the plasticizer bis (2-ethylhexyl) phthalate (DEHP) and other plasticizers in the
manufacture of plastic products has been restricted due to adverse health outcomes such as …
manufacture of plastic products has been restricted due to adverse health outcomes such as …
The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice
T Streidl, I Karkossa, RR Segura Munoz, C Eberl… - Gut …, 2021 - Taylor & Francis
Extibacter muris is a newly described mouse gut bacterium which metabolizes cholic acid
(CA) to deoxycholic acid (DCA) via 7α-dehydroxylation. Although bile acids influence …
(CA) to deoxycholic acid (DCA) via 7α-dehydroxylation. Although bile acids influence …
[HTML][HTML] A computational view on nanomaterial intrinsic and extrinsic features for nanosafety and sustainability
G Mancardi, A Mikolajczyk, VK Annapoorani, A Bahl… - Materials Today, 2023 - Elsevier
In recent years, an increasing number of diverse Engineered Nano-Materials (ENMs), such
as nanoparticles and nanotubes, have been included in many technological applications …
as nanoparticles and nanotubes, have been included in many technological applications …
Influence of size and phase on the biodegradation, excretion, and phytotoxicity persistence of single-layer molybdenum disulfide
W Zou, X Li, C Li, Y Sun, X Zhang, C Jin… - Environmental …, 2020 - ACS Publications
The increasing applications of single-layer molybdenum disulfide (SLMoS2) pose great
potential risks associated with environmental exposure. This study found that metallic-phase …
potential risks associated with environmental exposure. This study found that metallic-phase …
Bioinformatics and machine learning to support nanomaterial grouping
A Bahl, S Halappanavar, W Wohlleben, P Nymark… - …, 2024 - Taylor & Francis
Nanomaterials (NMs) offer plenty of novel functionalities. Moreover, their physicochemical
properties can be fine-tuned to meet the needs of specific applications, leading to virtually …
properties can be fine-tuned to meet the needs of specific applications, leading to virtually …