Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes
Observed in PRL Receptor Knockout Mice | Endocrine Reviews | Oxford Academic Skip to Main …

The protein hormone prolactin (PRL) was first discovered as an anterior pituitary factor
capable of stimulating milk production in mammals. We now know that PRL has over 300 …

I. Introduction PRL PL, and GH are homologous proteins that are thought to have arisen from
a common ancestral gene by two successive tandem duplications (Refs. 1–5; for review, see …

To date, growth hormone (GH) is known to contribute to seawater adaptation only in
salmonid fishes (primitive Euteleostei). Accordingly, the effects of homologous GH and two …

Prolactin (PRL) has one of the broadest ranges of functions of any vertebrate hormone, and
plays a critical role in regulating aspects of reproduction in widely divergent lineages …

A radioimmunoassay (RIA) for recombinant tilapia growth hormone (GH) was established
and validated. The ability of various hypothalamic factors to regulate GH secretion in the …

Ghrelin is a peptide secreted mainly by gastric parietal cells that may play a role in appetite
regulation. Circulating ghrelin is abruptly lowered by food intake, but factors involved in …

Abstract Growth hormone (GH), prolactin (PRL), prolactin 2 (PRL2) and somatolactin (SL)
belong to the same hormone family and have a wide repertoire of effects including …

It is increasingly clear that growth hormone (GH) has growth-promoting effects in fishes,
which are mediated in part by the insulin-like growth factor (IGF)-I. Growth-promoting actions …

Prolactin (PRL) plays a central role in freshwater (FW) adaptation in teleost fish. Evidence
now suggests that growth hormone (GH) acts in the seawater (SW) adaptation in at least …