Globally, as populations age there will be challenges and opportunities to deliver optimal
health care to senior citizens. Epilepsy, a condition characterised by spontaneous recurrent …

People with epilepsy—in particular, late-onset epilepsy of unknown aetiology—have an
elevated risk of dementia, and seizures have been detected in the early stages of Alzheimer …

Individuals with Down syndrome (DS) have an increased risk for epilepsy during the whole
lifespan, but especially after age 40 years. The increase in the number of individuals with DS …

People with Alzheimer's disease (AD) have significantly higher rates of subclinical and overt
epileptiform activity. In animal models, oligomeric Aβ amyloid is able to induce neuronal …

Objective To assess the risk of incident epilepsy among participants with prevalent dementia
and the risk of incident dementia among participants with prevalent epilepsy in the …

Objective To determine the risk of dementia after the development of late-onset epilepsy.
Methods We used data from the Atherosclerosis Risk in Communities (ARIC) cohort study …

Alzheimer's Disease (AD) and epilepsy are common neurological diseases. The prevalence
of epilepsy in AD patients is higher than in healthy subjects, but identifying the reasons for …

Importance The incidence of unprovoked seizures and epilepsy increases considerably in
late life, with approximately one-third of seizures being of unknown etiology. While …

Amyloid-β (Aβ) 1-40 and 1-42 peptides are key mediators of synaptic and cognitive
dysfunction in Alzheimer's disease (AD). Whereas in AD, Aβ is found to act as a pro …

Epilepsy and Alzheimer's disease (AD) incidence increases with age. There are reciprocal
relationships between epilepsy and AD. Epilepsy is a risk factor for AD and, in turn, AD is an …