Highlights•Autoimmunity is defined by a self-reactive adaptive immune system, causing
clinical pathology in autoimmune diseases.•Evidence suggests that autoimmunity and …

Silicosis is an ancient and potentially fatal pneumoconiosis caused by exposure to
respirable crystalline silica. Silicosis is historically a disease of miners; however, failure to …

Autoimmune diseases (ADs) are a broad spectrum of disorders featured by the body's
immune responses being directed against its own tissues, resulting in prolonged …

The intestinal microbiota plays a crucial role in influencing the development of host
immunity, and in turn the immune system also acts to regulate the microbiota through …

Objective. Growing evidence suggests increasing frequencies of autoimmunity and certain
autoimmune diseases, but findings are limited by the lack of systematic data and evolving …

Objectives To examine trends in the incidence of rheumatoid arthritis (RA) from 2005 to
2014 overall and by serological status as compared with 1995–2004 and 1985–1994 …

Inhalation of dust containing crystalline silica is associated with a number of acute and
chronic diseases including systemic autoimmune diseases. Evidence for the link with …

Background The majority of people live in cities and urbanization is continuing worldwide.
Cities have long been known to be society's predominant engine of innovation and wealth …

Sarcoidosis is a granulomatous inflammatory disease with unknown etiology.
Epidemiological studies have contributed greatly to our knowledge about sarcoidosis …

From the clinical standpoint, systemic sclerosis (SSc) is characterized by skin and internal
organ fibrosis, diffuse fibroproliferative vascular modifications, and autoimmunity. Clinical …