A framework for designing delivery systems

W Poon, BR Kingston, B Ouyang, W Ngo… - Nature …, 2020 - nature.com
The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing
and treating patients. Nanomaterials are promising vehicles to transport agents that include …

[HTML][HTML] Pharmaceutical electrospinning and 3D printing scaffold design for bone regeneration

Z Wang, Y Wang, J Yan, K Zhang, F Lin, L Xiang… - Advanced drug delivery …, 2021 - Elsevier
Bone regenerative engineering provides a great platform for bone tissue regeneration
covering cells, growth factors and other dynamic forces for fabricating scaffolds. Diversified …

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Synthesis and applications of anisotropic nanoparticles with precisely defined dimensions

AK Pearce, TR Wilks, MC Arno… - Nature Reviews Chemistry, 2021 - nature.com
Shape and size play powerful roles in determining the properties of a material; controlling
these aspects with precision is therefore an important, fundamental goal of the chemical …

Magnetic nanoparticles in targeted drug delivery: a review

E Kianfar - Journal of Superconductivity and Novel Magnetism, 2021 - Springer
Magnetic nanoparticles are one of the most important and widely used types of
nanomaterials, whose unique properties make them special compared to other …

Fabrication of bioinspired hydrogels: challenges and opportunities

H Fan, JP Gong - Macromolecules, 2020 - ACS Publications
Since the birth of synthetic hydrogel 60 years ago, hydrogels possessing various useful
properties and functions have been developed. The research directions of hydrogels have …

[HTML][HTML] Modulation of immune responses by particle size and shape

MV Baranov, M Kumar, S Sacanna… - Frontiers in …, 2021 - frontiersin.org
The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …

Photodegradation Elevated the Toxicity of Polystyrene Microplastics to Grouper (Epinephelus moara) through Disrupting Hepatic Lipid Homeostasis

X Wang, H Zheng, J Zhao, X Luo… - … Science & Technology, 2020 - ACS Publications
Microplastics (MPs) have caused increasing global concerns due to their detrimental effects
on marine ecosystems. However, the role of photodegradation in altering toxicity of MPs to …

Material design for lymph node drug delivery

A Schudel, DM Francis, SN Thomas - Nature Reviews Materials, 2019 - nature.com
A significant fraction of the total immune cells in the body are located in several hundred
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …

Near‐infrared‐light‐activatable nanomaterial‐mediated phototheranostic nanomedicines: an emerging paradigm for cancer treatment

R Vankayala, KC Hwang - Advanced Materials, 2018 - Wiley Online Library
Cancer is one of the most deadly diseases threatening the lives of humans. Although many
treatment methods have been developed to tackle cancer, each modality of cancer treatment …