The specific loss of midbrain dopamine neurons (mDANs) causes major motor dysfunction
in Parkinson's disease, which makes cell replacement a promising therapeutic approach …

Parkinson's disease (PD) stands as the second most common neurodegenerative disorder
after Alzheimer's disease, and its prevalence continues to rise with the aging global …

Induced pluripotent stem cells (iPSC) represent a potentially exciting regenerative-medicine
cell therapy for several chronic conditions such as macular degeneration, soft tissue and …

Parkinson's disease (PD) is a neurodegenerative disorder associated with loss of
dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). One strategy for …

Despite the fact that human neural cell models have played significant roles in both research
and cell replacement therapies for neurological diseases, the existing techniques for …

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder of the
central nervous system that results from the loss of dopaminergic (DA) nigral neurons …

Controllable drug delivery systems (DDS) can overcome the disadvantages of conventional
drug administration processes, such as high dosages or repeated administration. Herein, a …

人诱导多能干细胞体外定向分化为多巴胺能神经元祖细胞- PMC Back to Top Skip to main
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Dopamine is present in a subgroup of neurons that are vital for normal brain functioning.
Disruption of the dopaminergic system, eg, by chemical compounds, contributes to the …

Objective To establish an efficient protocol for directed differentiation of human induced
pluripotent stem cells (hiPSCs) into functional midbrain dopaminergic progenitor cells …