Recent advances in hyperthermia therapy‐based synergistic immunotherapy
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …
mRNA vaccine era—mechanisms, drug platform and clinical prospection
S Xu, K Yang, R Li, L Zhang - International journal of molecular sciences, 2020 - mdpi.com
Messenger ribonucleic acid (mRNA)-based drugs, notably mRNA vaccines, have been
widely proven as a promising treatment strategy in immune therapeutics. The extraordinary …
widely proven as a promising treatment strategy in immune therapeutics. The extraordinary …
A DNA nanodevice-based vaccine for cancer immunotherapy
S Liu, Q Jiang, X Zhao, R Zhao, Y Wang, Y Wang… - Nature Materials, 2021 - nature.com
A major challenge in cancer vaccine therapy is the efficient delivery of antigens and
adjuvants to stimulate a controlled yet robust tumour-specific T-cell response. Here, we …
adjuvants to stimulate a controlled yet robust tumour-specific T-cell response. Here, we …
The great immune escape: understanding the divergent immune response in breast cancer subtypes
Breast cancer, the most common type of cancer affecting women, encompasses a collection
of histologic (mainly ductal and lobular) and molecular subtypes exhibiting diverse clinical …
of histologic (mainly ductal and lobular) and molecular subtypes exhibiting diverse clinical …
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
The tumour microenvironment is the primary location in which tumour cells and the host
immune system interact. Different immune cell subsets are recruited into the tumour …
immune system interact. Different immune cell subsets are recruited into the tumour …
Cryomicroneedles for transdermal cell delivery
Cell therapies for the treatment of skin disorders could benefit from simple, safe and efficient
technology for the transdermal delivery of therapeutic cells. Conventional cell delivery by …
technology for the transdermal delivery of therapeutic cells. Conventional cell delivery by …
Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment
Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …
with normal tissue, the tumour microenvironment has some unique properties, such as …
Biomimetic nanotechnology toward personalized vaccines
While traditional approaches for disease management in the era of modern medicine have
saved countless lives and enhanced patient well‐being, it is clear that there is significant …
saved countless lives and enhanced patient well‐being, it is clear that there is significant …
Biomaterial-based scaffold for in situ chemo-immunotherapy to treat poorly immunogenic tumors
Poorly immunogenic tumors, including triple negative breast cancers (TNBCs), remain
resistant to current immunotherapies, due in part to the difficulty of reprogramming the highly …
resistant to current immunotherapies, due in part to the difficulty of reprogramming the highly …
A melanin-mediated cancer immunotherapy patch
Melanin is capable of transforming 99.9% of the absorbed sunlight energy into heat,
reducing the risk of skin cancer. We here develop a melanin-mediated cancer …
reducing the risk of skin cancer. We here develop a melanin-mediated cancer …