Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in
part can become irreversible to conventional therapies, defining the concept of airway …

Mast cells are (in) famous for their role in allergic diseases, but the physiological and
pathophysiological roles of this ingenious cell are still not fully understood. Mast cells are …

Cancer immunotherapy has opened a new landscape in cancer treatment, however, the
poor specificity and resistance of most targeted therapeutics have limited their therapeutic …

Mast cells (MCs) act as primary effectors in inflammatory and allergic reactions by releasing
intracellularly-stored inflammatory mediators in diseases. The two major pathways for MC …

Mast cells (MCs) are crucial cells participating in both innate and adaptive immune
processes that play important roles in protecting human health and in the pathophysiology of …

Chemokines are a class of small cytokines or signaling proteins that are secreted by cells.
Owing to their ability to induce directional chemotaxis of nearby responding cells, they are …

Hematopoietic stem cells (HSCs) are defined based on their capacity to replenish
themselves (self-renewal) and give rise to all mature hematopoietic cell types (multi-lineage …

Mast cells (MCs) are tissue-resident immune cells that are important players in diseases
associated with chronic inflammation such as cancer. Since MCs can infiltrate solid tumors …

Mast cells (MCs) are multifaceted innate immune cells often present in the tumor
microenvironment (TME). Several recent findings support their contribution to the transition …

Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating
leukocytes. While this scarcity long hampered basophil studies, innovations during the past …