Accelerated reaction kinetics in microdroplets: Overview and recent developments

Z Wei, Y Li, RG Cooks, X Yan - Annual Review of Physical …, 2020 - annualreviews.org
Various organic reactions, including important synthetic reactions involving C–C, C–N, and
C–O bond formation as well as reactions of biomolecules, are accelerated when the …

Ambient ionization mass spectrometry: recent developments and applications

CL Feider, A Krieger, RJ DeHoog… - Analytical chemistry, 2019 - ACS Publications
The early 2000s brought a new age in the field of mass spectrometry (MS) with the
introduction of ambient ionization MS techniques. As defined by one of its early visionaries …

[HTML][HTML] Advances in solid phase microextraction and perspective on future directions

N Reyes-Garces, E Gionfriddo… - Analytical …, 2017 - ACS Publications
Solid phase microextraction (SPME) is a versatile, nonex-haustive sample preparation tool
that has been demonstrated to be well-suited for facile and effective analysis of a broad …

Advances in mass spectrometry imaging for spatial cancer metabolomics

X Ma, FM Fernández - Mass spectrometry reviews, 2024 - Wiley Online Library
Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

[HTML][HTML] Targeting fatty acid metabolism in glioblastoma

J Miska, NS Chandel - The Journal of Clinical Investigation, 2023 - Am Soc Clin Investig
Glioblastoma (GBM) is a primary tumor of the brain defined by its uniform lethality and
resistance to conventional therapies. There have been considerable efforts to untangle the …

ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung

MJ Schuijs, S Png, AC Richard, A Tsyben… - Nature …, 2020 - nature.com
Metastasis constitutes the primary cause of cancer-related deaths, with the lung being a
commonly affected organ. We found that activation of lung-resident group 2 innate lymphoid …

Spatially resolved metabolomics to discover tumor-associated metabolic alterations

C Sun, T Li, X Song, L Huang, Q Zang… - Proceedings of the …, 2019 - National Acad Sciences
Characterization of tumor metabolism with spatial information contributes to our
understanding of complex cancer metabolic reprogramming, facilitating the discovery of …

Mass spectrometry using electrospray ionization

GRD Prabhu, ER Williams, M Wilm… - Nature Reviews Methods …, 2023 - nature.com
Applying a high voltage to a liquid passing through a capillary disintegrates the liquid
meniscus to generate a fine spray of charged droplets. As the droplets evaporate, polar …

[HTML][HTML] Spatial multi-omics analyses of the tumor immune microenvironment

WC Hsieh, BR Budiarto, YF Wang, CY Lin… - Journal of Biomedical …, 2022 - Springer
In the past decade, single-cell technologies have revealed the heterogeneity of the tumor-
immune microenvironment at the genomic, transcriptomic, and proteomic levels and have …

Quantitative mass spectrometry imaging of biological systems

D Unsihuay, D Mesa Sanchez… - Annual review of physical …, 2021 - annualreviews.org
Mass spectrometry imaging (MSI) is a powerful, label-free technique that provides detailed
maps of hundreds of molecules in complex samples with high sensitivity and subcellular …