Biomimetic engineered nanocarriers inspired by viruses for oral-drug delivery

JY Zhang, XX Liu, JY Lin, XY Bao, JQ Peng… - International Journal of …, 2022 - Elsevier
Oral administration is the most preferred and simplest route, but it is highly challenging due
to the numerous barriers in the gastrointestinal tract. To overcome these barriers …

Lassa virus glycoprotein complex review: insights into its unique fusion machinery

HN Pennington, J Lee - Bioscience Reports, 2022 - portlandpress.com
Lassa virus (LASV), an arenavirus endemic to West Africa, causes Lassa fever—a lethal
hemorrhagic fever. Entry of LASV into the host cell is mediated by the glycoprotein complex …

Screening and identification of Lassa virus entry inhibitors from an FDA-approved drug library

P Wang, Y Liu, G Zhang, S Wang, J Guo, J Cao… - Journal of …, 2018 - Am Soc Microbiol
Lassa virus (LASV) belongs to the Mammarenavirus genus (family Arenaviridae) and
causes severe hemorrhagic fever in humans. At present, there are no Food and Drug …

[HTML][HTML] Identification of the dietary supplement capsaicin as an inhibitor of Lassa virus entry

K Tang, X Zhang, Y Guo - Acta Pharmaceutica Sinica B, 2020 - Elsevier
The limited treatment options for the increasing occurrence of Lassa hemorrhagic fever in
West Africa poses an urgent need for the discovery and development of novel therapeutics …

Screening of botanical drugs against Lassa virus entry

Y Liu, J Guo, J Cao, G Zhang, X Jia, P Wang… - Journal of …, 2021 - Am Soc Microbiol
Lassa virus (LASV) belongs to the Old World genus Mammarenavirus (family Arenaviridae).
At present, there are no approved drugs or vaccines specific for LASV. In this study, high …

The antifungal isavuconazole inhibits the entry of lassa virus by targeting the stable signal peptide-GP2 subunit interface of lassa virus glycoprotein

X Zhang, K Tang, Y Guo - Antiviral Research, 2020 - Elsevier
Lassa virus (LASV) is the causative agent of Lassa hemorrhagic fever in humans, and the
limited therapeutic treatment for Lassa fever poses significant threat to public health in West …

[HTML][HTML] The Adaptive Immune Response against Bunyavirales

R Alatrash, BB Herrera - Viruses, 2024 - mdpi.com
The Bunyavirales order includes at least fourteen families with diverse but related viruses,
which are transmitted to vertebrate hosts by arthropod or rodent vectors. These viruses are …

[HTML][HTML] Screening and Identification of Lujo Virus Entry Inhibitors From an Food and Drug Administration-Approved Drugs Library

J Cao, S Dong, Y Liu, M Zhou, J Guo, X Jia… - Frontiers in …, 2021 - frontiersin.org
Lujo virus (LUJV) belongs to the Old World (OW) genus Mammarenavirus (family
Arenaviridae). It is categorized as a biosafety level (BSL) 4 agent. Currently, there are no US …

[HTML][HTML] Development of horse neutralizing immunoglobulin and immunoglobulin fragments against Junín virus

X Pan, Y Wu, W Wang, L Zhang, G Xiao - Antiviral research, 2020 - Elsevier
Argentine haemorrhagic fever (AHF) is a rodent-borne disease with a lethality as high as~
30%, which is caused by the New World arenavirus, Junín virus (JUNV). It was once a major …

Novel neutralizing monoclonal antibodies against Junin virus

X Pan, Y Wu, W Wang, L Zhang, G Xiao - Antiviral research, 2018 - Elsevier
Junin virus (JUNV) is the pathogen of Argentine haemorrhagic fever which results in high
lethality, while there is limited therapeutics available. Here, a series of mouse monoclonal …