Antigenicity and receptor affinity of SARS-CoV-2 BA. 2.86 spike
A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant, BA.
2.86, has emerged and spread to numerous countries worldwide, raising alarm because its …
2.86, has emerged and spread to numerous countries worldwide, raising alarm because its …
[HTML][HTML] Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking
SARS-CoV-2 continues to evolve, with many variants evading clinically authorized
antibodies. To isolate monoclonal antibodies (mAbs) with broadly neutralizing capacities …
antibodies. To isolate monoclonal antibodies (mAbs) with broadly neutralizing capacities …
An update on the anti-Spike monoclonal antibody pipeline for SARS-CoV-2
Abstract Background Anti-Spike monoclonal antibodies represent one of the most tolerable
prophylaxis and therapies for COVID-19 in frail and immunocompromised patients …
prophylaxis and therapies for COVID-19 in frail and immunocompromised patients …
Antibodies that neutralize all current SARS-CoV-2 variants of concern by conformational locking
SUMMARY SARS-CoV-2 continues to evolve and evade most existing neutralizing
antibodies, including all clinically authorized antibodies. We have isolated and …
antibodies, including all clinically authorized antibodies. We have isolated and …
[HTML][HTML] Humoral responses elicited by SARS-CoV-2 mRNA vaccine in people living with HIV
L Marchitto, D Chatterjee, S Ding, G Gendron-Lepage… - Viruses, 2023 - mdpi.com
While mRNA SARS-CoV-2 vaccination elicits strong humoral responses in the general
population, humoral responses in people living with HIV (PLWH) remain to be clarified …
population, humoral responses in people living with HIV (PLWH) remain to be clarified …
Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys
C Fenwick, P Turelli, Y Duhoo, K Lau, C Herate… - Journal of Infection, 2023 - Elsevier
Objectives Due to the rapid evolution of SARS-CoV-2 to variants with reduced sensitivity to
vaccine-induced humoral immunity and the near complete loss of protective efficacy of …
vaccine-induced humoral immunity and the near complete loss of protective efficacy of …
[HTML][HTML] The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11
WD Tolbert, Y Chen, L Sun, M Benlarbi, S Ding… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2, the virus behind the COVID-19 pandemic, has changed over time to the extent
that the current virus is substantially different from what originally led to the pandemic in …
that the current virus is substantially different from what originally led to the pandemic in …
[HTML][HTML] A Candidate DNA Vaccine Encoding the Native SARS-CoV-2 Spike Protein Induces Anti-Subdomain 1 Antibodies
A Frische, V Gunalan, KA Krogfelt, A Fomsgaard… - Vaccines, 2023 - mdpi.com
The ideal vaccine against viral infections should elicit antibody responses that protect
against divergent strains. Designing broadly protective vaccines against SARS-CoV-2 and …
against divergent strains. Designing broadly protective vaccines against SARS-CoV-2 and …
Epitopes of an antibody that neutralizes a wide range of SARS-CoV-2 variants in a conserved subdomain 1 of the spike protein
H Ishimaru, M Nishimura, H Shigematsu… - Journal of …, 2024 - Am Soc Microbiol
The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
continued, enabling the virus to escape from host immunity by changing its spike antigen …
continued, enabling the virus to escape from host immunity by changing its spike antigen …
[HTML][HTML] Differentiating Cell Entry Potentials of SARS-CoV-2 Omicron Subvariants on Human Lung Epithelium Cells
The surface spike (S) glycoprotein mediates cell entry of SARS-CoV-2 into the host through
fusion at the plasma membrane or endocytosis. Omicron lineages/sublineages have …
fusion at the plasma membrane or endocytosis. Omicron lineages/sublineages have …