4D flow MRI

M Markl, A Frydrychowicz, S Kozerke… - Journal of Magnetic …, 2012 - Wiley Online Library
Traditionally, magnetic resonance imaging (MRI) of flow using phase contrast (PC) methods
is accomplished using methods that resolve single‐directional flow in two spatial …

Advanced flow MRI: emerging techniques and applications

M Markl, S Schnell, C Wu, E Bollache, K Jarvis… - Clinical radiology, 2016 - Elsevier
Magnetic resonance imaging (MRI) techniques provide non-invasive and non-ionising
methods for the highly accurate anatomical depiction of the heart and vessels throughout the …

Mathematical modeling of thrombus formation in idealized models of aortic dissection: initial findings and potential applications

C Menichini, XY Xu - Journal of mathematical biology, 2016 - Springer
Aortic dissection is a major aortic catastrophe with a high morbidity and mortality risk caused
by the formation of a tear in the aortic wall. The development of a second blood filled region …

Giant intracranial aneurysms: evolution of management in a contemporary surgical series

ME Sughrue, D Saloner, VL Rayz, MT Lawton - Neurosurgery, 2011 - journals.lww.com
BACKGROUND: Many significant microsurgical series of patients with giant aneurysms
predate changes in practice during the endovascular era. OBJECTIVE: A contemporary …

Multi-indicator analysis of mechanical blood damage with five clinical ventricular assist devices

Y Li, H Wang, Y Xi, A Sun, X Deng, Z Chen… - Computers in biology and …, 2022 - Elsevier
Purpose Device-induced blood damage contributes the hemolysis, thrombosis and bleeding
complications in patients supported with ventricular assist device (VAD). This study aims to …

Association of wall shear stress with intracranial aneurysm rupture: systematic review and meta-analysis

G Zhou, Y Zhu, Y Yin, M Su, M Li - Scientific reports, 2017 - nature.com
To evaluate the relationship between wall shear stress (WSS) magnitude and cerebral
aneurysm rupture and provide new insight into the disparate computational fluid dynamics …

In-silico trial of intracranial flow diverters replicates and expands insights from conventional clinical trials

A Sarrami-Foroushani, T Lassila, M MacRaild… - Nature …, 2021 - nature.com
The cost of clinical trials is ever-increasing. In-silico trials rely on virtual populations and
interventions simulated using patient-specific models and may offer a solution to lower these …

Shape optimization of pulsatile ventricular assist devices using FSI to minimize thrombotic risk

CC Long, AL Marsden, Y Bazilevs - Computational Mechanics, 2014 - Springer
In this paper we perform shape optimization of a pediatric pulsatile ventricular assist device
(PVAD). The device simulation is carried out using fluid–structure interaction (FSI) modeling …

Calcific aortic stenosis—a review on acquired mechanisms of the disease and treatments

B Zebhi, M Lazkani, D Bark Jr - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Calcific aortic stenosis is a progressive disease that has become more prevalent in recent
decades. Despite advances in research to uncover underlying biomechanisms, and …

Bypass surgery for the treatment of dolichoectatic basilar trunk aneurysms: a work in progress

MT Lawton, AA Abla, WC Rutledge, A Benet… - …, 2016 - journals.lww.com
BACKGROUND: The treatment of dolichoectatic basilar trunk aneurysms has been
ineffectual or morbid due to nonsaccular morphology, deep location, and involvement of …