Therapeutically harnessing extracellular vesicles
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …
from the study of fundamental biology to a subject of significant clinical relevance. The …
Aptamer-based detection of circulating targets for precision medicine
L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
The tumor microenvironment: a milieu hindering and obstructing antitumor immune responses
A Labani-Motlagh, M Ashja-Mahdavi… - Frontiers in …, 2020 - frontiersin.org
The success of cancer immunotherapy relies on the knowledge of the tumor
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …
Shedding light on extracellular vesicle biogenesis and bioengineering
F Teng, M Fussenegger - Advanced Science, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are biocompatible, nano‐sized secreted vesicles containing
many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their …
many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their …
Prevalence and disease burden of chronic kidney disease
JC Lv, LX Zhang - Renal fibrosis: mechanisms and therapies, 2019 - Springer
Chronic kidney disease (CKD) has been recognized as a leading public health problem
worldwide. The global estimated prevalence of CKD is 13.4%(11.7–15.1%), and patients …
worldwide. The global estimated prevalence of CKD is 13.4%(11.7–15.1%), and patients …
Exosome-mediated metastasis: communication from a distance
Metastasis, a critical phase of tumor progression, remains a primary challenge in treating
cancer and a major cause of cancer mortality. Cell-cell communication via extracellular …
cancer and a major cause of cancer mortality. Cell-cell communication via extracellular …
The role of lipids in exosome biology and intercellular communication: Function, analytics and applications
Exosomes are extracellular vesicles that in recent years have received special attention for
their regulatory functions in numerous biological processes. Recent evidence suggests a …
their regulatory functions in numerous biological processes. Recent evidence suggests a …
New technologies for analysis of extracellular vesicles
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
Extracellular vesicles as tools and targets in therapy for diseases
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
[HTML][HTML] Biogenesis and function of extracellular vesicles in cancer
Extracellular vesicles (EVs) are heterogeneous multi-signal messengers that support cancer
growth and dissemination by mediating the tumor-stroma crosstalk. Exosomes are a subtype …
growth and dissemination by mediating the tumor-stroma crosstalk. Exosomes are a subtype …