Several groups have provided evidence that positron emission tomography (PET) and
single-photon emission computed tomography (SPECT) neuroreceptor imaging techniques …

Abnormalities of dopamine function in schizophrenia are suggested by the common
antidopaminergic properties of antipsychotic medications. However, direct evidence of a …

The modulating effects of serotonin on dopamine neurotransmission are not well
understood, particularly in acute psychotic states. Positron emission tomography was used …

Dopamine neurotransmission is associated with high susceptibility to cocaine abuse.
Positron emission tomography was used in 12 rhesus macaques to determine if dopamine …

Neurotransmitters as electrochemical signaling molecules are essential for proper brain
function and their dysfunction is involved in several mental disorders. Therefore, the …

Since their discovery in the mammalian brain, it has been apparent that serotonin (5-HT)
and dopamine (DA) interactions play a key role in normal and abnormal behavior …

OBJECTIVE: The authors investigated whether striatal dopamine D2 receptor binding
characteristics in vivo are similar in men and women and whether there are sex-related …

The present study evaluated, via a combined electrophysiological and dialysis approach,
the potential influence of serotonin (5‐HT) 2C as compared to 5‐HT2A and 5‐HT2B …

The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with
modern instrumentation are key components to successful developments in PET. Clever …

This article reviews the receptor pharmacology of neuroleptics, with a focus on newer drugs
(eg, risperidone, olanzapine, sertindole, quetiapine, and ziprasidone) in contrast to older …