Phytochemicals and their metabolites are not considered essential nutrients in humans,
although an increasing number of well-conducted studies are linking their higher intake with …

Gene–nutrient interactions are important contributors to health management and disease
prevention. Nutrition can alter gene expression, as well as the susceptibility to disease …

Osteosarcoma is the most common primary solid tumor of bone. It has a high metastatic
potential and occurs predominantly in adolescents and young adults. Angiopoietin 2 …

Abstract Programmed cell death-1 (PDCD1/PD-1) and its ligand programmed cell death 1
ligand 1 (CD274/PD-L1) have been reported to suppress anti-tumor T cell-mediated immune …

Postoperative recurrence and metastasis are the main reasons for the poor prognosis of
osteosarcoma (OS). Currently, an ideal predictor for not only prognosis but also drug …

Introduction: Epidemiological studies indicate that diet rich in fruits and vegetables is
associated with decreased cancer risk thereby indicating that dietary polyphenols can be …

In recent years, much research has focused on the role of angiogenesis in osteosarcoma,
which occurs predominantly in adolescents and young adults. The vascular endothelial …

Resistin is an adipokine that is associated with obesity, inflammation, and various cancers.
Chondrosarcomas are primary malignant bone tumors that have a poor prognosis. VEGF-A …

Chondrosarcoma is the second most common primary malignancy of bone after myeloma
and osteosarcoma. Chondrosarcoma development may be linked to angiogenesis, which is …

Abstract Casein kinase 2 (CK2) plays a critical role in the proliferation and apoptosis of
cancer cells. Resveratrol is a bioactive compound with anticancer and anti-inflammatory …