Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches

R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …

Emerging role of circulating microRNA in the diagnosis of human infectious diseases

R Ojha, R Nandani, RK Pandey… - Journal of cellular …, 2019 - Wiley Online Library
The endogenic microRNAs (miRNA) are evolutionary, conserved, and belong to a group of
small noncoding RNAs with a stretch of 19–24 nucleotides. The miRNAs play an …

Designing multi-epitope vaccine against Staphylococcus aureus by employing subtractive proteomics, reverse vaccinology and immuno-informatics approaches

MT ul Qamar, S Ahmad, I Fatima, F Ahmad… - Computers in Biology …, 2021 - Elsevier
Staphylococcus aureus is a deadly human bacterial pathogen that causes a wide variety of
clinical manifestations. Invasive S. aureus infections in hospitals and the community are one …

Immunoinformatics and molecular docking studies reveal a novel Multi-Epitope peptide vaccine against pneumonia infection

SR Mahapatra, J Dey, T Kaur, R Sarangi, AA Bajoria… - Vaccine, 2021 - Elsevier
Pneumonia is a major endemic disease around the world, and an effective vaccine is the
need of the hour to fight against the disease. When there are no appropriate antiviral and …

Structural basis and designing of peptide vaccine using PE-PGRS family protein of Mycobacterium ulcerans—An integrated vaccinomics approach

Z Nain, MM Karim, MK Sen, UK Adhikari - Molecular Immunology, 2020 - Elsevier
Buruli ulcer is an emerging tissue-necrosis infectious disease, caused by the pathogen
Mycobacterium ulcerans, leading to permanent deformity if untreated. Despite this …

Exploring lassa virus proteome to design a multi-epitope vaccine through immunoinformatics and immune simulation analyses

SB Sayed, Z Nain, MSA Khan, F Abdulla… - International Journal of …, 2020 - Springer
Lassa virus (LASV) is responsible for a type of acute viral haemorrhagic fever referred to as
Lassa fever. Lack of adequate treatment and preventive measures against LASV resulted in …

Design of a multi-epitope vaccine against cervical cancer using immunoinformatics approaches

S Sanami, F Azadegan-Dehkordi… - Scientific Reports, 2021 - nature.com
Cervical cancer, caused by human papillomavirus (HPV), is the fourth most common type of
cancer among women worldwide. While HPV prophylactic vaccines are available, they have …

Immunoinformatics and structural aided approach to develop multi-epitope based subunit vaccine against Mycobacterium tuberculosis

G Sethi, RP Varghese, AK Lakra, SS Nayak… - Scientific Reports, 2024 - nature.com
Tuberculosis is a highly contagious disease caused by Mycobacterium tuberculosis (Mtb),
which is one of the prominent reasons for the death of millions worldwide. The bacterium …

Recent advances in the development of protein-and peptide-based subunit vaccines against tuberculosis

C Bellini, K Horvati - Cells, 2020 - mdpi.com
The World Health Organization (WHO) herald of the “End TB Strategy” has defined goals
and targets for tuberculosis prevention, care, and control to end the global tuberculosis …