Amoebiasis is the second leading cause of death from parasitic disease worldwide. The
causative protozoan parasite, Entamoeba histolytica, is a potent pathogen. Secreting …

Parasitic diseases represent major global health problems of immense proportion.
Schistosomiasis, malaria, leishmaniasis, Chagas disease, and African sleeping sickness …

Invasion causes cancer malignancy. We review recent data about cellular and molecular
mechanisms of invasion, focusing on cross-talk between the invaders and the host. Cancer …

Amebiasis in developed countries is most common in im-migrants and travelers returning
from the third world, and less common in men who have sex with men and …

In order for the protozoan parasite Entamoeba histolytica (Eh) to cause invasive intestinal
and extraintestinal infection, which leads to significant morbidity and mortality, it must disrupt …

Amebiasis is a major cause of morbidity and mortality throughout the tropical world.
Entamoeba histolytica is now recognized as a separate species from the morphologically …

▪ Abstract Proteases from a variety of protozoan parasites have been characterized at the
molecular and cellular levels, and the many roles that proteases play in these organisms are …

Cysteine proteases are known to be important pathogenicity factors of the protozoan
parasite Entamoeba histolytica. So far, a total of eight genes coding for cysteine proteases …

The parasite Entamoeba histolytica is named for its ability to lyse host tissues. To determine
the factors responsible, we have initiated an examination of the contribution of parasite …

Here, we present evidence that a cysteine protease (EhCP112) and a protein with an
adherence domain (EhADH112) form the Entamoeba histolytica 112 kDa adhesin …