Biofabrication of silver nanoparticles using Praecitrullus fistulosus fruit extract exhibits in vitro antibacterial and anticancer activity

CS Madhu, KS Balaji, J Shankar, SNS Gowda… - Journal of Drug Delivery …, 2022 - Elsevier
The silver nanoparticles were synthesized using green mediated approach aided by the fruit
of extract of Praecitrullus fistulosus to evaluate its biological properties. The synthesized …

Musa acuminata lectin exerts anti-cancer effects on HeLa and EAC cells via activation of caspase and inhibitions of Akt, Erk, and Jnk pathway expression and …

BK Srinivas, MC Shivamadhu, S Jayarama - International Journal of …, 2021 - Elsevier
In the present study aimed to purify the lectin from the sap of Musa acuminata pseudostem
and elucidate the apoptotic and angiogenic molecular mechanism in both in-vitro and in …

Angiosuppressive effects of bio-fabricated silver nanoparticles synthesis using Clitoria ternatea flower: an in vitro and in vivo approach

BK Srinivas, MC Shivamadhu, KK Siddappaji… - JBIC Journal of …, 2019 - Springer
Biosynthesis of silver nanoparticles (CTNP's) by Clitoria ternatea flower in the aqueous
extract was investigated. Synthesized nanoparticles were characterized by using UV–Visible …

2,4‐Bis(2‐(E)‐arylidenehydrazinyl)quinazolines: Expeditious Synthesis, Characterization, Antiproliferative Effects against Breast Cancer Cell Line and Molecular …

R Kumar, V Kumar, R Kamal, A Kumar, S Kaur… - …, 2022 - Wiley Online Library
Considering the immense significance of molecular hybridization in development of
efficacious antiproliferative agents, the present research work demonstrates the expeditious …

Antitumor effects of chitin specific lectin from Praecitrullus fistulosus by targeting angiogenesis and apoptosis

CS Madhu, KS Balaji, J Shankar… - … and Biophysical Research …, 2019 - Elsevier
In the present study, chitin specific lectin was purified from fruit exudates of Praecitrullus
fistulosus. The lectin was purified and analyzed using affinity chromatography, RP-HPLC …

Acid‐Catalysed Cyclization of o‐Aminobenzamide with α‐Oxodithioesters: A Divergent and Regioselective Synthesis of Quinazolinones and 1,3‐Benzothiazinones

KR Kiran, TR Swaroop, R Preetham… - …, 2023 - Wiley Online Library
Acid catalysed cyclization of o‐aminobenzamide and α‐oxodithioesters in a highly
regioselective fashion to give 2‐aroylquinazolin‐4 (3H)‐ones and 2‐aroyl‐4H‐benzo [d][1 …

PIFA Mediated Synthesis of Bis‐1, 2, 4‐triazoloquinazolines as Potential Anticancer Agents on MCF‐7 Cancer Cells: Characterization, Molecular Docking …

R Kumar, O Bains, R Kamal, A Kumar, S Kaur… - …, 2023 - Wiley Online Library
A novel series of bis ([1, 2, 4] triazolo)[4, 3‐a][4′, 3′‐c] quinazolines derivatives 2 a–2 o
has been synthesis in good to excellent yields (74–86%) under mild reaction conditions via …

Diversely Functionalized Pyridine Ring-fused Heterocycles and their Anticancer Properties

KH Narasimhamurthy, YR Girish… - Letters in Drug …, 2024 - ingentaconnect.com
Among N-containing heterocycles, pyridine occupies a prominent position due to its
presence in nature. Many enzymes in living systems, which are involved in redox reactions …

Novel Synthetic Indazoles Abrogate Angiogenesis in Erlich Ascites Tumor Bearing Mice

N Ashwini, KS Balaji, BL Sadashivaiah… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Background: Indazoles are known for their anti-cancer properties. Objective: The current
investigation was on the synthesis and evaluation of novel indazole derivatives for their …

Angio-Suppressive Effect of Partially Purified Lectin-like Protein from Musa acuminata pseudostem by Inhibition of VEGF-Mediated Neovascularization and Induces …

BK Srinivas, MC Shivamadhu, S Jayarama - Nutrition and cancer, 2019 - Taylor & Francis
Lifestyle and nutritional changes have contributed much to the somatic genetic changes
which have concurrently led to an increase cancer in humans. Hence the plant-based and …