Human embryonic stem cells (HESCs) are the in vitro descendants of the pluripotent inner
cell mass (ICM) of human blastocyst stage embryos. HESCs can be kept undifferentiated in …

Brain ischemic stroke is one of the most common causes of death and disability, currently
has no efficient therapeutic strategy in clinic. Due to irreversible functional neurons loss and …

Transplantation of human embryonic stem cells (hESC) into immune-deficient mice leads to
the formation of differentiated tumors comprising all three germ layers, resembling …

In the interest of public safety, the Food and Drug Administration (FDA) has jurisdiction over
the production and marketing of any stem-cell–based therapy involving the transplantation …

One of the exciting advances in modern medicine and life science is cell-based
neurovascular regeneration of damaged brain tissues and repair of neuronal structures. The …

Cellular cardiomyoplasty is an attractive option for the treatment of severe heart failure. It is,
however, still unclear and controversial which is the most promising cell source. Therefore …

The potential for the formation of teratomas or other neoplasms is a major safety roadblock
to clinical application of pluripotent stem cell therapies. Preclinical assessment of the risk of …

Future therapeutic applications of differentiated human embryonic stem cells (hESC) carry a
risk of teratoma formation by contaminating undifferentiated hESC. We generated 10 …

Although basic research on human embryonic stem cells (hESCs) at the laboratory bench
has progressed with enviable speed there has been little head way in terms of its clinical …

Incredible strides have been made since the discovery of insulin almost 100 years ago.
Insulin formulations have improved dramatically, glucose levels can be measured …