Cognitive reserve (CR) may reduce the risk of dementia. We summarized the effect of CR on
progression to mild cognitive impairment (MCI) or dementia in studies accounting for …

Background Morning cortisol levels have been reported to be elevated among patients with
Alzheimer's disease (AD); yet no meta-analysis has been conducted to confirm the existence …

Introduction Elevated cortisol levels have been reported in Alzheimer's disease (AD) and
may accelerate the development of brain pathology and cognitive decline …

Introduction 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is an intracellular
enzyme that catalyses conversion of cortisone into cortisol; correspondingly, 11β-HSD1 …

The aging of the population, which is accompanied by an increasing prevalence of
Alzheimer disease (AD), makes it imperative to identify factors that reduce risk of onset of …

Background Many clinical studies have shown a correlation between plasma cortisol and
neurological disorders. This study explored the causal relationship between plasma cortisol …

Introduction Several lifestyle factors promote protection against Alzheimer's disease (AD)
throughout a person's lifespan. Although such protective effects have been described for …

Epidemiological studies are associating elevated exposure to air pollution with increased
risk of Alzheimer's disease and other neurodegenerative disorders. In effect, air pollution …

How excessive stress and cortisol exposure predispose people to clinical Alzheimer's
disease (AD) is a matter of great potential medical impact. We discuss recent findings …

Background: Late-life depression (LLD) is related to an increased risk of developing
dementia; however, the biological mechanisms explaining this relationship remain unclear …