Common causes of hearing loss in humans-exposure to loud noise or ototoxic drugs and
aging-often damage sensory hair cells, reflected as elevated thresholds on the clinical …

Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Sensory organ damage induces a host of cellular and physiological changes in the
periphery and the brain. Here, we show that some aspects of auditory processing recover …

Cochlear synaptopathy can result from various insults, including acoustic trauma, aging,
ototoxicity, or chronic conductive hearing loss. For example, moderate noise exposure in …

Noise-induced cochlear synaptopathy has been demonstrated in numerous rodent studies.
In these animal models, the disorder is characterized by a reduction in amplitude of wave I of …

Objectives: Recent animal studies demonstrated that cochlear synaptopathy, a partial loss of
inner hair cell-auditory nerve fiber synapses, can occur in response to noise exposure …

Hearing loss caused by exposure to recreational and occupational noise remains a
worldwide disabling condition and dysregulation of redox homeostasis is the hallmark of …

Evidence from animal and human studies suggests that moderate acoustic exposure,
causing only transient threshold elevation, can nonetheless cause “hidden hearing loss” that …

Aging listeners, even in the absence of overt hearing loss measured as changes in hearing
thresholds, often experience impairments processing temporally complex sounds such as …

Auditory perception is our main gateway to communication with others via speech and
music, and it also plays an important role in alerting and orienting us to new events. This …