This review provides an update of the genetic content, phylogeny and evolution of the family
Adenoviridae. An appraisal of the condition of adenovirus genomics highlights the need to …

Adenoviruses have served as a model for investigating viral-cell interactions and
discovering different cellular processes, such as RNA splicing and DNA replication. In …

Human adenoviral (HAd) vectors have demonstrated great potential as vaccine vectors.
Preclinical and clinical studies have demonstrated the feasibility of vector design, robust …

New advances in the field of genetic characterization of adenoviruses originating from
different animal species are summarized. Variations seen in the host range and specificity …

Adenoviruses are one of the most genetically diverse DNA viruses and cause non-
lifethreatening infections in the ocular, respiratory, or gastrointestinal epithelium of a diverse …

The genome of frog adenovirus (FrAdV-1) was sequenced and found to be the smallest of all
known adenovirus genomes. The sequence obtained was 26163 bp in size and contains a …

Recombinant fowl adenoviruses (FAdVs) have been successfully used as veterinary vaccine
vectors. However, insufficient definitions of the protein-coding and non-coding regions and …

Cancer is one of the leading causes of death in the world, which is the second after heart
diseases. Adenoviruses (Ads) have become the promise of new therapeutic strategy for …

Importance of the field: With the emergence of highly pathogenic avian influenza H5N1
viruses that have crossed species barriers and are responsible for lethal infections in …

Although recombinant human adenovirus (HAV)-based vectors offer several advantages for
somatic gene therapy and vaccination over other viral vectors, it would be desirable to …