In this review the available reports on drug resistance in human helminths, particularly
hookworms and schistosomes, are critically analyzed. The experiences with helminths of …

Background Extensive use of praziquantel for treatment and control of schistosomiasis
requires a comprehensive understanding of efficacy and safety of various doses for different …

Recent evidence suggest that resistance to praziquantel (PZQ) may be developing. This
would not be surprising in countries like Egypt where the drug has been used aggressively …

To determine if resistance/tolerance to the antischistosomal drug praziquantel (PZQ) is
appearing in Egyptian villages within the Nile delta region, where it has been used …

Background Children carry most of the schistosomiasis burden. While school-aged children
are the principal target group of preventive chemotherapy with praziquantel, limited …

Praziquantel has been the mainstay of schistosomiasis control since 1984 and widely
distributed since 2006 through 'preventive chemotherapy'programmes to school-aged …

Virtually all the important helminth infections in humans can be treated with one of 5
anthelmintics currently in use: albendazole, mebendazole, diethylcarbamazine, ivermectin …

Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as
preventive chemotherapy as part of national helminth control strategies. Given the heavy …

Background Schistosoma mansoni is a parasitic infection common in the tropics and sub‐
tropics. Chronic and advanced disease includes abdominal pain, diarrhoea, blood in the …

Each year, millions of African children receive praziquantel (PZQ) by mass drug
administration (MDA) to treat schistosomiasis at a standard single dose of 40 mg/kg of body …