Lung endothelia in the arteries, capillaries, and veins are heterogeneous in structure and
function. Lung capillaries in particular represent a unique vascular niche, with a thin yet …

Short chain fatty acids (SCFA) are metabolites of intestinal bacteria resulting from
fermentation of dietary fiber. SCFA are protective in various animal models of inflammatory …

Helicobacter pylori colonization of the human stomach can lead to adverse clinical
outcomes including gastritis, peptic ulcers, or gastric cancer. Current data suggest that in …

Purpose: We determine the changes in intestinal microbiota and/or disruptions in intestinal
homeostasis during uveitis. Methods: Experimental autoimmune uveitis (EAU) was induced …

Helicobacter pylori is a Gram-negative bacterium that infects the gastric epithelia of its
human host. Everyone who is colonized with these pathogenic bacteria can develop gastric …

Diverse pathogens are detected in Alzheimer's disease (AD) brains. A bioinformatics survey
showed that AD genome-wide association study (GWAS) genes (localized in bone marrow …

Severe bacterial (pneumococcal) infections are commonly associated with influenza and are
significant contributors to the excess morbidity and mortality of influenza. Disruption of lung …

Infectious diseases and cancers are leading causes of death and pose major challenges to
public health. The human peptidome encompasses millions of compounds that display an …

Granulomas are important immunological structures in the host defense against the fungus
Paracoccidioides brasiliensis, the main etiologic agent of Paracoccidioidomycosis (PCM), a …

Cryptococcus species are encapsulated fungi found in the environment that predominantly
cause disease in immunocompromised hosts after inhalation into the lungs. Even with …