Integrins are a family of transmembrane glycoprotein signaling receptors that can transmit
bioinformation bidirectionally across the plasma membrane. Integrin αIIbβ3 is expressed at a …

Integrins are vital surface adhesion receptors that mediate interactions between the
extracellular matrix (ECM) and cells and are essential for cell migration and the …

Integrin receptors provide a dynamic, tightly-regulated link between the extracellular matrix
(or cellular counter-receptors) and intracellular cytoskeletal and signalling networks …

The integrin family of transmembrane adhesion receptors is essential for sensing and
adhering to the extracellular environment. Integrins are heterodimers composed of non …

Integrins are transmembrane cell–adhesion molecules that carry signals from the outside to
the inside of the cell and vice versa. Like other cell surface receptors, integrins signal in …

Cells recognize and respond to their extracellular environment through transmembrane
receptors such as integrins, which physically connect the extracellular matrix to the …

T-cell acute lymphoblastic leukemia (T-ALL) accounts for 15% and 25% of total childhood
and adult ALL cases, respectively. During T-ALL, patients are at risk of organ infiltration by …

Focal adhesions (FAs) are protein machineries essential for cell adhesion, migration, and
differentiation. Talin is an integrin-activating and tension-sensing FA component directly …

Interaction of cells with the extracellular matrix is fundamental to a wide variety of biological
processes, such as cell proliferation, cell migration, embryogenesis, and organization of …

Integrins are essential adhesion receptors found on the surfaces of all metazoan cells. As
regulators of cell migration and extracellular matrix assembly, these membrane-spanning …